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Isaiah Spiller RB | LV
Chargers' Isaiah Spiller: Garners 44 total yards in debut
Spiller rushed 10 times for 34 yards and brought in his only target for 10 yards in the Chargers' 29-22 preseason loss to the Rams on Saturday night.
The rookie fourth-round pick saw his first carry with 4:39 remaining in the first half as the third running back in, and he ended up pacing the Chargers in carries and rushing yards. While Spiller wasn't exactly efficient on the ground, he was also playing behind an assortment of second- and third-team offensive linemen. Spiller remains in a battle with the likes of Joshua Kelley and Larry Rountree for positioning behind Austin Ekeler, and he should have ample opportunity to make his case again in next Saturday night's home preseason clash against the Cowboys.
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Marlon Mack RB | ARI
Texans' Marlon Mack: Starts in preseason opener
Mack carried the ball three times for six yards in Saturday's 17-13 preseason win over the Saints.
Mack drew the start at running back with the Texans' first-team offense on the field for the opening two series, but only one of his three carries went for more than three yards as the unit struggled to move the ball early. Rookie fourth-rounder Dameon Pierce eventually impressed as he paced the backfield with five rushes for 49 yards while Mack looked on, which could help the former earn some run with the ones this coming Friday against the Rams. However, Mack remains atop the depth chart at running back for the time being.
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Rico Dowdle RB | PIT
Cowboys' Rico Dowdle: Opens preseason loss as starter
Dowdle (illness) rushed nine times for 36 yards in the Cowboys' 17-7 preseason loss to the Broncos on Saturday night.
Dowdle fared reasonably well with his opportunities and paced the Cowboys in carries on the night. The 24-year-old Dowdle and undrafted rookie Malik Davis, his primary competitor for the No. 3 running back job, were similarly productive, so their job battle will continue in next Saturday night's road exhibition matchup against the Chargers.
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Zack Moss RB | CIN
Bills' Zack Moss: Looks good in preseason action
Moss gained 37 yards on three carries in Saturday's 27-24 preseason victory over the Colts. He also chipped in two receptions on three targets for five yards.
With Devin Singletary held out of the game, Moss was the first back on the field for Buffalo. He began the contest with two rushes of five yards but proceeded to rip off a 27-yard gain on a play that was originally designed to go up the middle. However, Moss was able to bounce off of a tackle and turn the corner for a big gain. After the exhibition, coach Sean McDermott complimented Moss's growth, both on and off the field, per Dan Fetes of ABC Rochester. Singletary is almost certain to begin the season as Buffalo's lead back, though Moss could hold off rookie James Cook for a secondary role in the backfield.
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James Cook RB | BUF
Bills' James Cook: Minimal impact in preseason debut
Cook carried the ball three times for five yards in Saturday's 27-24 preseason win over the Colts. He added one reception on one target for five yards.
Cook mixed in with Zack Moss on the Bills' first offensive possession of the game and was on the field for a few offensive possessions thereafter. He couldn't get going in any facet of the game and was outplayed by Moss, who managed 37 yards on three attempts. Devin Singletary didn't suit up Saturday but is expected to serve as the lead back in Buffalo to begin the season, while Moss and Cook figure to battle for a complementary role out of the backfield.
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Rachaad White RB | WAS
Buccaneers' Rachaad White: Posts 88 all-purpose yards in debut
White rushed seven times for 32 yards, brought in two of three targets for 13 yards and returned two kickoffs for 43 yards in the Buccaneers' 26-24 preseason loss to the Dolphins on Saturday night.
White was the third running back into the game for the Buccaneers behind Giovani Bernard and Ke'Shawn Vaughn, and he outproduced the latter by four yards with three fewer touches from scrimmage. White, a third-round rookie, gave a rock-solid accounting of himself in his first taste of NFL action, even flashing nicely on special teams with a 26-yard kickoff return. White and Vaughn will continue their summer battle for the No. 2 running back job in next Saturday night's preseason road matchup against the Titans.
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Kenneth Walker III RB | KC
Seahawks' Kenneth Walker: Logs six touches Saturday
Walker rushed five times for 19 yards while securing his lone target for 11 yards during the Seahawks' 32-25 preseason loss to the Steelers on Saturday.
Walker served as a starter during Saturday's preseason opener since Rashaad Penny (groin) was kept off the field. Although Walker didn't reach the end zone, he was involved in the Seahawks' offense over the first few drives of the game. The 2022 second-round pick has drawn plenty of praise from coach Pete Carroll over the first few weeks of training camp, particularly for his abilities in the passing game. While Penny is a strong candidate to start if he's healthy once the regular season begins, Walker should also be in the mix for touches, especially if he continues to develop as a receiver and pass blocker.
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Ke'Shawn Vaughn RB | SF
Buccaneers' Ke'Shawn Vaughn: Logs 12 touches in opener
Vaughn rushed 10 times for 19 yards and a touchdown and brought in both targets for 22 yards in the Buccaneers' 26-24 preseason loss to the Dolphins on Saturday night.
Vaughn was the second running back in for the Buccaneers behind Giovani Bernard, and although the former accomplished next to nothing on the ground, he did power into the end zone from one yard out with 6:34 remaining in the second quarter. Vaughn did have some success as a receiver, but he didn't keep up on per-touch production with his primary competitor for the No. 2 running back job, Rachaad White. The battle between Vaughn and White will be one to watch through the remainder of the summer and will feature its next installment in next Saturday night's road matchup against the Titans.
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Marlon Mack RB | ARI
Texans' Marlon Mack: In line to play Saturday
Mack is slated to play in Saturday's preseason contest versus the Saints, Aaron Wilson of ProFootballNetwork.com reports.
Meanwhile, Rex Burkhead is not expected to suit up. Notably, Mack was listed as the top running back on the Texans' first unofficial depth chart, so it stands to reason the coaching staff may hold a different view on the situation. In any case, rookie fourth-rounder Dameon Pierce will sub in for Mack and likely get a fair amount of action before halftime, while the team's remaining healthy RBs are Dare Ogunbowale, Royce Freeman and BJ Emmons.
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Benny Snell RB | DET
Steelers' Benny Snell: Not likely to suit up Saturday
Snell (knee) is unlikely to play in Saturday's preseason game versus the Seahawks, Brooke Pryor of ESPN.com reports.
Snell took a seat at Thursday's practice, where he was seen with a large wrap on his right knee. That was scaled down to a sleeve by Saturday, but he wasn't in uniform ahead of the contest. It's unclear if top running back Najee Harris will join Snell in street clothes, but if both sit out, the Steelers backfield will consist of Anthony McFarland, Jaylen Warren, Mataeo Durant and Master Teague.