Brooks is being evaluated for a possible concussion and is questionable to return to Sunday's game against the Patriots.

Brooks appeared to get shaken up on the opening kickoff of the second half and is being evaluated by medical staff to determine whether he can return. With Samaje Perine (ankle) inactive, practice squad running back Gary Brightwell will provide backfield depth behind Chase Brown for as long as Brooks is out of the game.

White (coach's decision) is inactive for Sunday's matchup with the Browns.

White will be a healthy scratch for the sixth consecutive game. Ashton Jeanty, Raheem Mostert and Dylan Laube are ahead of him on the depth chart. White has just 10 carries for 25 yards and no touchdowns in 2025.

Sanders (coach's decision) is inactive for Sunday's matchup against the Raiders.

Sanders hasn't played since the Browns' Week 1 loss to the Bengals, where he rushed three times on three snaps. The team will go with a three-man backfield with Quinshon Judkins, Jerome Ford and Dylan Sampson again.

Holani (hamstring) has been ruled out for the rest of Sunday's game against the Titans, Brady Henderson of ESPN.com reports.

Holani sustained the injury in the first half, which has been deemed too severe by medical staff for him to return to Sunday's game. Kenneth Walker and Zach Charbonnet will be the two Seahawks running backs the rest of the way, and with Holani out and Dareke Young (quadriceps) on injured reserve, wide receivers Cody White and Rashid Shaheed should handle return duties on kickoffs.

Gray (knee) is active for Sunday's game against the Lions, Dan Salomone of the Giants' official site reports.

Gray was activated off the Giants' reserve/PUP list Saturday, and the third-year running back has been cleared to make his 2025 regular-season debut Sunday. He will serve as the team's RB3 behind Tyrone Tracy and Devin Singletary.

Vaki (ankle) is active for Sunday's game against the Giants.

Vaki will once again be the primary depth option behind Jahmyr Gibbs and David Montgomery at the running back position. The rookie has climbed the depth chart by being a strong kick return option as well as running back, and if Gibbs or Montgomery were to go down, Vaki would be next up for the Lions' offense.

Reynolds (coach's decision) is inactive for Sunday's game against the Giants.

Reynolds will be a healthy scratch for consecutive weeks, with the team seemingly continuing to try rookie running back Sione Vaki at third-string running back and as the second kick returner. The Lions will once again roll with Jahmyr Gibbs, David Montgomery, Sione Vaki and Jacob Saylors at running back for Sunday's game.

Herbert (coach's decision) is inactive for Sunday's game against the Ravens.

Herbert was unavailable the past two games due to a groin injury but will be inactive again Sunday despite being recovered from the injury. Kene Nwangwu will instead serve as the No. 3 tailback behind Breece Hall and Isaiah Davis.

Nwangwu (hamstring) is active for Sunday's game against Baltimore.

Nwangwu was limited in the last two practices of Week 12 prep due to a hamstring injury, but he has been given the green light to play Sunday after going through pregame warmups. Nwangwu will mostly contribute on special teams as a returner on kickoffs, but he will also will serve as the Jets' No. 3 RB behind Breece Hall and Isaiah Davis due to Khalil Herbert (coach's decision) being inactive.

Mullings (ankle) is active for Sunday's game against the Seahawks.

Mullings was activated off injured reserve Saturday in anticipation for Sunday's contest, his first game since Week 3 against the Colts. The rookie sixth-rounder has worked his way back from an ankle injury he sustained in that Week 3 loss and will take his place behind Tony Pollard and Tyjae Spears as the third running back for the Titans' offense.