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Marcus Mariota QB | WAS
Commanders' Marcus Mariota: Won't return Sunday
Mariota (knee) has been ruled out for the remainder of Sunday's game against the Colts in London, Tashan Reed of The Washington Post reports.
Mariota left the game midway through the first quarter, after he appeared to injure his right knee on a sack. With Jayden Daniels (elbow) inactive for a second straight game and with Mariota -- who previously dealt with an MCL sprain in the same knee during the preseason -- set to miss the final two quarters of Sunday's contest, rookie seventh-round pick Athan Kaliakmanis will be the lone healthy quarterback available for Washington. Mariota will finish Week 4 with three completions on four attempts for 46 yards and one carry for 35 yards.
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Marcus Mariota QB | WAS
Commanders' Marcus Mariota: Managing knee injury, uncertain to return
The Commanders list Mariota as questionable to return to Sunday's game against the Colts in London due to a knee injury.
Mariota appeared to injure his right knee when he was sacked with 7:05 remaining in the first quarter. As Tashan Reed of The Washington Post notes, Mariota dealt with an MCL sprain in the same knee during the preseason, but it's unclear at this point whether he's dealing with any sort of related setback. With Jayden Daniels (elbow) inactive for a second straight game, the Commanders would be left with Athan Kaliakmanis as their lone healthy quarterback if Mariota is unable to continue. Reserve tight end Colson Yankoff would be an emergency option at quarterback for Washington if Kaliakmanis also departs with an injury at any point, per Nicki Jhabvala of The Athletic.
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Marcus Mariota QB | WAS
Commanders' Marcus Mariota: Makes visit to locker room Sunday
Mariota sustained an undisclosed injury in the first quarter of Sunday's game against the Colts in London and headed to the locker room for further evaluation, Nicki Jhabvala of The Athletic reports.
Making a second straight start in place of Jayden Daniels (elbow), Mariota completed three of four pass attempts for 46 yards and ran once for a 35-yard gain before he appeared to get hurt on a third-down sack with 7:05 remaining in the quarter. Athan Kaliakmanis came on to replace Mariota under center on the Commanders' next possession.
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Andy Dalton QB | ATL
Eagles' Andy Dalton: Slides to third on depth chart
Dalton is expected to serve as the Eagles' No. 3 quarterback for Sunday's game against the Rams, while Tanner McKee moves up to second on the depth chart as the top backup to Jalen Hurts, Mike Garafolo of NFL Network reports.
Dalton had been active ahead of McKee as the No. 2 quarterback for each of the Eagles' first three games of the season, but he didn't see any action until midway through the second quarter of Monday's 27-7 loss to the Bears, when Hurts exited to get checked for a concussion. After three consecutive handoffs to Saquon Barkley got the Eagles to two-yard line to set up a third-and-goal, Dalton proceeded to throw a back-breaking interception in the end zone on his lone pass attempt before Hurts returned for the ensuing possession. The costly pick looks to have been enough to cost Dalton the No. 2 job, at least for one week.
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Tanner McKee QB | PHI
Eagles' Tanner McKee: Replacing Dalton as No. 2 quarterback
McKee is expected to be active for Sunday's game against the Rams as the top backup to starter Jalen Hurts, while Andy Dalton serves as the Eagles' No. 3 quarterback, Mike Garafolo of NFL Network reports.
Despite operating as Hurts' primary backup in 2025, McKee slid to third on the depth chart entering the 2026 season after the Eagles acquired Dalton in a trade with the Panthers back in March. Dalton didn't see any snaps on the season until midway through the second quarter of Monday's 27-7 loss to the Bears, when Hurts made a brief exit from the contest to get checked for a concussion. After three consecutive Saquon Barkley carries got the Eagles near the goal line, Dalton proceeded to throw a costly interception in the end zone on his lone pass attempt before Hurts returned for the next possession. The gaffe appears to have resulted in Dalton turning the backup gig over to McKee, at least for one week.
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Baker Mayfield QB | TB
Buccaneers' Baker Mayfield: Could miss up to six weeks
Mayfield's dislocated right thumb could keep him out anywhere from 3-to-6 weeks, depending on how quickly he's able to resume gripping the football without issue, Adam Schefter of ESPN reports.
Head coach Todd Bowles previously acknowledged that Mayfield would miss at least three weeks due to the injury, which he sustained in last Sunday's loss to the Vikings. Though Mayfield was cleared of any tendon or ligament damage and won't need surgery on the thumb on his throwing hand, the two-time Pro Bowler required stitches to close a wound caused by the dislocation. Despite facing a loose recovery timeline that could keep him out for more than four games, Mayfield avoided placement on injured reserve Saturday, which signals that the Buccaneers are still holding out hope that he might be ready to go after a three-week absence. For however long Mayfield ends up being sidelined, the Buccaeneers will turn to undrafted rookie Jalon Daniels to direct the offense, beginning with Sunday's game versus Green Bay.
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Riley Leonard QB | IND
Colts' Riley Leonard: No. 3 quarterback for Week 4
Leonard is inactive for Sunday's game against the Commanders in London as the Colts' emergency No. 3 quarterback.
Leonard hasn't been active for any of the Colts' first four games after Anthony Richardson beat him out for the No. 2 job coming out of the preseason. The second-year player out of Notre Dame will only be available in the event both starter Daniel Jones and Richardson are unable to finish the game.
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Anthony Richardson QB | IND
Colts' Anthony Richardson: Remaining No. 2 quarterback
Richardson is active for Sunday's game against the Commanders in London.
Richardson has yet to take any snaps this season, but he'll suit up for a fourth straight game as Daniel Jones' backup after securing the No. 2 job coming out of the preseason. Meanwhile, second-year player Riley Leonard will be inactive as the Colts' emergency No. 3 quarterback.
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Jake Haener QB | NYG
Giants' Jake Haener: Elevated, likely to be backup QB in Week 4
The Giants elevated Haener from their practice squad Saturday, Dan Salomone of the Giants' official site reports.
Haener was active for last Sunday's win against Tennessee but didn't get into the game. He was subsequently waived Monday after New York traded for J.J. McCarthy, but Haener then rejoined New York as part of the team's practice squad Wednesday. His elevation for Week 4 likely means Haener will back up Jameis Winston for a second straight week, as Jordan Raanan of ESPN.com notes that McCarthy likely hasn't yet had enough time to familiarize himself with the Giants' playbook.
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Easton Stick QB | TB
Buccaneers' Easton Stick: Set to work as No. 2 QB in Week 4
The Buccaneers elevated Stick from their practice squad to their active roster Saturday ahead of Sunday's matchup against Green Bay, Scott Smith of the team's official site reports.
Stick signed with Tampa Bay's practice squad in early September to serve as organizational QB depth. He'll now get a chance to be active on game day due to starter Baker Mayfield being set to miss multiple weeks with a thumb injury. Undrafted rookie Jalon Daniels is slated to start behind center during Mayfield's absence, and Stick will provide a veteran option -- albeit one with only six career games of regular-season action -- should Daniels need to exit or struggle significantly.