Player Bio
| HT/WT: 6-4, 263 lbs |
| Birthplace: Athens, GR |
| Age: 25 |
| School: Purdue |
| Experience: 5 |
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Top George Karlaftis News
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Chiefs' George Karlaftis: Played through broken hand in 2025
Defensive line coach Joe Cullen said Wednesday that Karlaftis played multiple games with a broken hand in 2025, Pete Sweeney of The Kansas City Star reports.
Despite the serious injury he apparently sustained prior to Week 11 at Denver, Karlaftis missed only one game last season, sitting out in Week 18 when the Chiefs were already eliminated from playoff contention. Now fully healthy, he projects to again play a huge role on the edge for Kansas City in 2026.
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Chiefs' George Karlaftis: Posts career-high stops in 2025
Karlaftis accumulated 48 tackles (25 solo), including 6.0 sacks, two pass defenses and one fumble recovery across 16 games in 2025 with the Chiefs.
The fourth-year pro looked like he was on his way to a career year after opening the season with 4.5 sacks and 20 combined tackles through the first five games of the regular season. Karlaftis wasn't able to carry that momentum for the rest of 2025, but his combined tackles were one more than his previous career high set in 2023 (across 16 regular-season games). The 2022 first-rounder signed a four-year, $93 million contract extension in July and will be a cornerstone of the Chiefs' defense for years to come.
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Chiefs' George Karlaftis: Unavailable for Week 18
Karlaftis (rest) is inactive for Sunday's contest against the Raiders, Matt McMullen of the Chiefs' official site reports.
Karlaftis will get a breather in the regular-season finale with Kansas City already eliminated from the postseason. In his absence, Charles Omenihu is a top candidate to take over as a starter on the defensive line versus Las Vegas.
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Chiefs' George Karlaftis: Questionable yet healthy
Karlaftis (rest) is listed as questionable ahead of Sunday's game against the Raiders.
Karlaftis was a limited participant throughout Week 18, but his injury status is listed as non-injured rest. The defensive end signed a four-year, $93 million contract with the Chiefs in July. The team may just be looking to protect a valuable asset ahead of the 2026 season, as Kansas City missed the playoffs for the first time since the 2014 campaign. If Karlaftis is inactive for Sunday's game, he will end the season with 48 tackles (25 solo), including 6.0 sacks, and two passes defensed through 16 games.
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Chiefs' George Karlaftis: Active for Week 17
Karlaftis (illness) is active for Thursday night's game against the Broncos.
Karlaftis will be good to go for Week 17 after being added to the injury report with an illness Wednesday. The defensive lineman has compiled 46 total tackles (24 solo), including 6.0 sacks, while also adding two passes defensed and a fumble recovery over 15 games so far this year.
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Chiefs' George Karlaftis: Under the weather, iffy for Week 17
Karlaftis (illness) is listed as questionable for Thursday's game against Denver.
Karlaftis popped up on Wednesday's injury report as a limited practice participant due to an illness, which puts him in jeopardy of playing Christmas Day. Charles Omenihu, Ashton Gillotte, Mike Pennel and Jerry Tillery would be in line for larger rotational roles on the defensive line if one or both of Karlaftis and Derrick Nnadi (illness) were unable to play.
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