Guyton is dealing with a high-ankle sprain and likely won't be available for Sunday's matchup against the Chiefs, Todd Archer of ESPN.com reports.

The second-year pro from Oklahoma exited the Week 12 win over the Eagles with an ankle injury and is now expected to sidelined for the Week 13 matchup as well. While Guyton recovers, Nate Thomas is likely to step in and start at left tackle.

Coach Kevin Stefanski named Sanders as the Browns' starting quarterback for next Sunday's game against the 49ers.

Even though Dillon Gabriel cleared concussion protocol Monday, Sanders will get the nod against San Francisco after he helped guide the Browns to a 24-10 over the Raiders on Sunday. Sanders completed 11 of 20 passes (55 percent) for 209 yards, one touchdown and one interception against Las Vegas, showing some deep-ball touch on a 52-yard shot to Isaiah Bond down to the two-yard line in the process. Sanders' matchup against the Niners will be favorable on paper, as San Francisco is dealing with a boat load of injuries on the defensive side of the ball, but it's fair to question if Sanders has enough of a floor-ceiling combo to warrant consideration for fantasy lineups.

Branch tallied seven total tackles (three solo) and one pass defensed in Sunday's 34-27 overtime win over the Giants.

The third-year pro from Alabama tied Amik Robertson for the second-most tackles on the Lions defense during Sunday's win, trailing Jack Campbell's 11-stop performance. Branch has appeared in 10 games for the Lions this season, recording 59 total tackles, including 2.5 sacks, and six passes defensed. He's expected to remain one of the team's top defensive playmakers in the Week 13 matchup against the Packers.

Gabriel cleared the concussion protocol Monday, Mary Kay Cabot of The Cleveland Plain Dealer reports.

However, Gabriel is expected to lose his starting job to Shedeur Sanders, who is likely to be named the Browns' QB1 for next Sunday's Week 13 game versus San Francisco, according to Ian Rapoport of NFL Network. Gabriel showed very little in his time under center, refusing to challenge defenses deep or away from the line of scrimmage, resulting in a 5.1 yards per pass attempt. Across eight games this season, including six starts, Gabriel has completed just 59.2 percent of his 184 pass attempts for 937 yards, seven touchdowns and two interceptions. He's averaged just 117.1 passing yards per game. The Browns will now take a longer look at Sanders to see if either one of the rookies is a viable long-term solution headed into 2026.

Pratt had 20 total tackles, two tackles for a loss and a pass defensed in Sunday's loss at Kansas City.

Pratt has been a revelation since taking over a starting linebacker role opposite Zaire Franklin after Joe Bachie went down with an injury and was later released. He played on 83 of the defense's 96 snaps in the overtime loss.

Corum rushed seven times for 24 yards during Sunday's 34-7 victory against the Buccaneers.

While the final score was another blowout win for the Rams, Tampa Bay successfully snuffed out the Rams' rushing attack; Corum and Kyren Williams combined for just 70 yards and no touchdowns on 19 attempts. After seeing double-digit touches for a three-week stretch, Corum's usage has dropped the past two weeks, with just 15 rushing attempts for 34 yards in that span. The Rams travel to take on the Carolina Panthers in Week 13, and they have been middle-of-the-road against the run in 2025, surrendering 113.1 yards per game on the ground.

Harper tallied six total tackles (five solo) and two passes defensed, including one interception, in Sunday's 34-27 overtime win over the Giants.

The second-year pro from Notre Dame made an impact while starting in place of the injured Kerby Joseph (knee) in Week 12, picking off Jameis Winston in the fourth quarter. Harper has now started five games in a row for the Lions, recording 22 total tackles and three passes defensed, including an interception, during that span. He could remain the starter at free safety if Joseph is unable to return for the Week 13 matchup against the Packers on Thursday.

Sanders will be named the Browns' starting quarterback for Week 13 against the 49ers, Ian Rapoport of NFL Network reports.

Even with Dillon Gabriel clearing the concussion protocol, according to Mary Kay Cabot of The Cleveland Plain Dealer, coach Kevin Stefanski is expected to name Sanders as the Browns' starter against San Francisco. Sanders made his first career start in Sunday's 24-10 win over the Raiders, completing just 11 of 20 passes (55 percent) for 209 yards, one touchdown and one interception. His 52-yard deep shot to Isaiah Bond was easily Sanders' most impressive throw of the day, as Dylan Sampson did all the work after the catch on a 66-yard touchdown that came on a dump-off at the line of scrimmage. Sanders will have a chance to build on his performance against a depleted and injury-riddled 49ers defense next Sunday. Sanders carries extremely minimal fantasy value.

Campbell recorded 11 total tackles (five solo) in Sunday's 34-27 overtime win over the Giants.

Campbell led Detroit's defense in total tackles Sunday and has now recorded double-digit stops in four of the team's last eight games. Through 11 appearances this season, the 2023 first-round pick has tallied 108 total tackles (third-most in the NFL), including 4.0 sacks, two forced fumbles and one pass defensed. He's expected to remain one of the NFL's premier inside linebackers and a viable IDP choice in the Week 13 matchup against the Packers.

Freiermuth secured all three of his targets for 19 yards and a touchdown during Sunday's 31-28 loss to Chicago.

Although Freiermuth continued to split work at tight end in Week 12, he scored a touchdown in the fourth quarter to bring the Steelers within three points. The touchdown was his fourth of the season, but he's now been held under 20 receiving yards in back-to-back weeks. Freiermuth's fantasy potential this season has been dependent on his ability to reach the end zone, and he's secured 26 of 32 targets for 298 yards and four scores over his first 11 appearances in 2025.