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Jordan Addison WR | MIN
Vikings' Jordan Addison: Will be Vikes' top WR for Week 4
Addison will serve as the Vikings' top wide receiver against the Dolphins on Sunday due to the absence of Justin Jefferson (ankle), Craig Peters of the Vikings' official site reports.
Jefferson injured his ankle during the first half of the Vikings' Week 3 win over the Buccaneers. That allowed Addison to take over as the WR1, and he finished that game with five catches (on nine targets) for 90 yards and a touchdown. The Dolphins have been a top-5 defense against wide receivers this season, but Addison should still see a healthy amount of targets from Kyler Murray in Jefferson's absence, with Jauan Jennings, Tai Felton and tight end T.J. Hockenson also in the mix for more passes.
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Marquise Brown WR | PHI
Eagles' Hollywood Brown: Out again in Week 4
Brown (ankle) is listed as out ahead of Sunday's game against the Rams.
Brown didn't practice all week and will now miss his second game of the 2026 campaign. With DeVonta Smith (hamstring) ruled out, Brown could have had an enhanced role if he was cleared to play in Week 4. However, with Brown, Smith and Dallas Goedert (knee) all on the shelf, Dontayvion Wicks and Makai Lemon will likely serve as Jalen Hurts' primary receiving options.
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Davante Adams WR | LAR
Rams' Davante Adams: Reverting back to WR2 vs. Philadelphia
Adams will serve as the Rams' WR2 against the Eagles on Sunday after Puka Nacua (hip) was cleared to play, Stu Jackson of the Rams' official site reports.
After a quiet Week 1 against the 49ers in Australia, Adams has put together a 15-332-2 receiving line (23 targets) over the Rams' last two games in the absence of Nacua. The latter does not carry an injury designation for Week 4, though Sarah Barshop of ESPN.com relays that the Rams are still figuring out what kind of snap count that Nacua will operate under in his return. Given that, Adams still figures to be a top target for Matthew Stafford in the passing game, particularly in the red zone, where Adams has thrived for his entire NFL career.
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Germie Bernard WR | PIT
Steelers' Germie Bernard: Two catches vs. Cleveland
Bernard caught both of his passes for 11 yards during the Steelers' 27-24 loss to the Browns on Thursday.
Bernard was not targeted by Aaron Rodgers until late in the fourth quarter, with the duo connecting on passes for six and five yards to help set up a three-yard touchdown catch by Pat Freiermuth after the two-minute warning. The rookie second-rounder was on the field for 29 of the Steelers' 72 offensive snaps (40.3 percent), which was third-most among wide receivers behind DK Metcalf (70) and Michael Pittman (52) and ahead of Roman Wilson (22). Bernard has a 7-60-0 receiving line on 11 targets through four regular-season games, though his role in the offense will be limited behind Metcalf, Pittman, Freiermuth, Darnell Washington and Jaylen Warren. The Steelers head back home for Week 5 against the Cotls on Sunday, Oct. 11.
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Brenen Thompson WR | LAC
Chargers' Brenen Thompson: Ruled out for Week 4
Thompson (quadriceps) has been ruled out for Sunday's game against the Seahawks.
Thompson will miss a second consecutive game while working through a quadriceps injury. He was unable to practice during Week 4 prep, so a limited session ahead of Week 5 against the Broncos would indicate that the rookie fourth-rounder is progressing in his recovery. Marquez Valdes-Scantling and Derius Davis will both work in rotational roles behind Ladd McConkey (foot), Quentin Johnston and Tre' Harris in Thompson's absence.
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Michael Pittman WR | PIT
Steelers' Michael Pittman: Quiet in loss Thursday night
Pittman caught two of four targets for 15 yards Thursday in a loss to the Browns.
Pittman logged a 72 percent offensive snap share, second-most among Pittsburgh wideouts, but he didn't do much with the ample playing time. In fact, Roman Wilson -- who logged a 22 percent offensive snap share -- outproduced Pittman considerably with a 3-74-1 receiving line. In his first season with the Steelers, Pittman has had a tough time connecting with QB Aaron Rodgers, posting just seven catches on 12 targets for 89 yards through three games. He'll look to make more of an impact in Week 5 against Indianapolis next Sunday.
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Chris Moore WR | BAL
Ravens' Chris Moore: Tagged as questionable for Week 4
Moore (ankle) is questionable for Sunday's game against the Titans.
Moore has been working through an ankle injury as of late, though he was able to play in the Ravens' Week 3 win over the Cowboys in Brazil. He's draw the questionable tag for Week 4, and if he's not cleared to play against Tennessee, then LaJohntay Wester and Elijah Sarratt would both be in line for a slight uptick in offensive snaps. Moore has accumulated three catches (on six targets) for 63 yards and a touchdown along with 229 yards on eight kickoff returns through three regular-season games.
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Dont'e Thornton Jr. WR | LV
Raiders' Dont'e Thornton: Could return to practice ahead of Week 5
Head coach Klint Kubiak said Friday that the hope is that Thornton (undisclosed) will be back at practice for practice ahead of the Raiders' Week 5 road tilt against the Patriots, Levi Edwards of the Raiders' official site reports.
Thornton opened the season on injured reserve due to an undisclosed injury that prevented him from participating in the majority of August practices during training camp. Once he's cleared to return, Thornton will likely operate in a depth role at wide receiver behind Tre Tucker, Jalen Nailor and Cody White.
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Christian Kirk WR | SF
49ers' Christian Kirk: Aiming for practice return in two weeks
Head coach Kyle Shanahan said Friday that the 49ers could open Kirk's (calf) practice window to return from injured reserve in two weeks, Matt Barrows of The Athletic reports.
Shanahan reiterated that Kirk is unlikely to be back at practice next week but is aiming to start participating in sessions following the 49ers' Week 5 tilt against the Seahawks. Kirk opened the season on injured reserve due to a calf injury he sustained in training camp in late July. The 49ers' WR room has been decimated by injuries, with Kirk, Demarcus Robinson (ankle), Ricky Pearsall (knee) and rookie second-rounder De'Zhaun Stribling (ankle) all on IR, and veteran Mike Evans injured his ribs during a Week 3 win over the Cardinals. Given the timeline Shanahan provided, it seems Kirk could be available as soon as Week 6 against the Commanders on Monday, Oct. 19.
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Mike Evans WR | SF
49ers' Mike Evans: Game-time decision incoming
Coach Kyle Shanahan said Friday that Evans (ribs) will be a game-time decision for Sunday's contest against the Broncos, Vic Tafur of The Athletic reports.
Officially, Evans is listed as questionable for Week 4 after failing to practice Wednesday and Thursday, per Cam Inman of The San Jose Mercury News. Evans is nursing a strained rib, and with a 4:25 p.m. ET kickoff incoming Sunday, there will be fewer options to pivot to for fantasy purposes if he ends up inactive. Currently, Deebo Samuel, Brandin Cooks, Jacob Cowing and Jordan Watkins are the healthy wide receivers on the 49ers' active roster.