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Brandon Aiyuk WR | SF
49ers' Brandon Aiyuk: Ditches hamstring injury
Aiyuk (hamstring) wasn't listed on the 49ers' injury report Wednesday.
Aiyuk missed his first potential game as a professional this past Sunday, but the 2020 first-round pick now is poised to make his debut this weekend against the Jets. With the hamstring injury behind him, he may serve as one of Jimmy Garoppolo's top receivers right away. Not only is Deebo Samuel (foot) on injured reserve, but stud tight end George Kittle is tending to a sprained left knee. Currently, Kendrick Bourne, Aiyuk, Trent Taylor, Dante Pettis and newcomer Mohamed Sanu are the healthy wide receivers on the 49ers' roster.
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Nick Westbrook-Ikhine WR | IND
Titans' Nick Westbrook-Ikhine: Earns promotion Wednesday
Tennessee promoted Westerbrook-Ikhine to its 53-man roster Wednesday, Jim Wyatt of the team's official site reports
The rookie out of Indiana got the call after he was shifted back to the practice roster Tuesday. With the team opening up a roster spot after waiving receiver Cody Hollister, Westbrook-Ikhine earned another shot. He failed to suit up in Monday's game against Denver as a healthy scratch, but he'll hope to make his NFL debut Sunday against Jacksonville.
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Equanimeous St. Brown WR | SF
Packers' Equanimeous St. Brown: Limited practice Wednesday
St. Brown practiced in a limited capacity Wednesday due to a knee injury, Rob Demovsky of ESPN.com reports.
St. Brown wasn't affected by an injury at all last week, only to be declared inactive for the season opener at Minnesota. Just days removed from that deactivation, he's tending to a knee injury. With his health somewhat compromised at the moment, it's difficult to project when he'll get to connect with Aaron Rodgers this season. St. Brown is firmly behind Davante Adams, Allen Lazard, Marquez Valdes-Scantling and Malik Taylor on Green Bay's depth chart at wide receiver.
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Jamison Crowder WR | WAS
Jets' Jamison Crowder: Limited in practice Wednesday
Crowder (hamstring) was a limited participant in Wednesday's practice, Rich Cimini of ESPN.com reports.
Crowder was also listed with a hamstring injury last week but logged a full slate of practices, so Wednesday's limited session stands out as something to monitor. He'll have two more opportunities to increase his level of activity ahead of Sunday's game against the 49ers. With Le'Veon Bell (hamstring) on IR for at least three weeks, Crowder could be in line to see an uptick in targets, but opposing defenses may also now be free to focus on shutting him down.
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Corey Davis WR | NYJ
Titans' Corey Davis: Dealing with hamstring issue
Davis didn't practice Wednesday due to a hamstring injury, Jim Wyatt of the Titans' official site reports.
Davis was initially listed as questionable ahead of Monday's win against the Broncos due to the hamstring injury, but he managed to play through the issue and racked up seven catches for 101 yards. As long as Davis is able to resume practicing Thursday, there won't be any real reason to worry about his status for Sunday's game against the Jaguars. If he's indeed cleared to suit up against Jacksonville, Davis will get a prime opportunity to keep the momentum going versus an inexperienced secondary.
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Brandin Cooks WR | SF
Texans' Brandin Cooks: Limited at practice
Cooks (quadriceps) logged a limited practice Wednesday.
Cooks headed into this past Thursday's season opener against the Chiefs listed as questionable, but he suited up and started, en route to catching two of his five targets for 20 yards, while seeing action on 31 of Houston's snaps on offense. With some added recovery time since then and a practice (albeit limited) to start his preparation for Sunday's game against the Ravens, it looks like Cooks will be able to give it a go again Week 2 against a Baltimore defense that was dominant in Week 1's 38-6 win over Cleveland.
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A.J. Brown WR | NE
Titans' A.J. Brown: Limited with knee injury
Brown (knee) was a limited participant in Wednesday's practice, Jim Wyatt of the Titans' official site reports.
Brown appears to have picked up a knee injury during Monday's win over the Broncos, during which he was held to 39 receiving yards while taking a backseat in the passing game to fellow wideout Corey Davis. With Davis not practicing to begin the week due to a hamstring injury, Brown could end up in position to draw increased targets Sunday against Jacksonville's inexperienced secondary, assuming he can move past his own knee issue.
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Diontae Johnson WR | CLE
Steelers' Diontae Johnson: Doesn't practice Wednesday
Johnson (toe) didn't practice Wednesday.
Nor did JuJu Smith-Schuster (knee), but both players logged 55 of a possible 64 snaps on offense in Monday's win over the Giants, so it's possible that the Steelers are simply managing the reps of a couple of key players dealing with opening-game aches and pains. Added clarity on that front will arrive no later than Thursday, when the team resumes preparations for Sunday's tilt against the Broncos. Johnson was targeted a team-high 10 times Week 1, yielding six catches for 57 yards.
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Jalen Reagor WR | MIA
Eagles' Jalen Reagor: Avoids injury report entirely
Reagor isn't listed on Wednesday's injury report.
Reagor initially looked in line to miss a handful of games due to the shoulder injury he suffered in late August, but he comfortably beat his projected recovery timetable and was able to play in the Eagles' Week 1 loss to Washington. Based on his complete lack of an injury designation to kick off Week 2, the rookie won't even have his practice reps affected by the shoulder issue. Reagor flashed his big-play ability with a 55-yard grab during his NFL debut, but he also failed to haul in any of his other three targets and muffed a punt. He'll look to turn in a more consistent performance Sunday against the Rams.
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JuJu Smith-Schuster WR | NYG
Steelers' JuJu Smith-Schuster: Sits out practice
Smith-Schuster didn't practice Wednesday due to a knee injury.
Fellow starting wideout Diontae Johnson (toe) also missed practice Wednesday. Smith-Schuster logged 55 of 64 offensive snaps in Monday's win over the Giants, catching all six of his targets for 69 yards and two scores. The Steelers may just have been holding him out of practice Wednesday for maintenance-related reasons, a notion that would be confirmed if Smith-Schuster practices in any capacity Thursday. With both Smith-Schuster and Johnson sitting out Wednesday, added practice reps were available for wideouts James Washington, Chase Claypool and Ray-Ray McCloud.