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Kerwynn Williams RB | KC
Cardinals' Kerwynn Williams: Expected to play Sunday
Williams (quadriceps/ribs) is expected to play Sunday against the Giants, Adam Schefter of ESPN reports.
Williams was listed as questionable on the official injury report when he was able to upgrade to a limited practice Friday after sitting out back-to-back sessions to begin the week. Though it sounds like he's not 100 percent, Williams should operate as the Cardinals' lead back if he plays. He draws an attractive matchup against a Giants defense that has surrendered 117.9 rushing yards per game and six rushing touchdowns over the past seven contests.
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Latavius Murray RB | BUF
Vikings' Latavius Murray: Totals 75 yards from scrimmage
Murray notched 21 carries for 69 yards and caught his sole target for six yards during Saturday's 16-0 win in Green Bay.
Murray's 22 touches outpaced all of his teammates by a long shot. As evidence, his four first-down runs were exactly half of Jerick McKinnon's entire workload (seven carries, one reception). Murray has now churned out 20-plus rushes in three of the last five games, a span in which he's averaged 76 yards from scrimmage per contest and two touchdowns. Due to the pounding taken during that stretch, he may be given a respite Week 17 if the Vikings lock up the No. 2 seed in the NFC playoffs by the end of this weekend.
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Aaron Jones RB | MIN
Packers' Aaron Jones: Will stay on sidelines for rest of night
Jones (knee) is out for the rest of Saturday's game against the Vikings.
With Jones out, fellow rookie Jamaal Williams will likely play a hefty majority of the snaps in Green Bay's backfield. Jones will finish the game with three carries for 13 yards.
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Aaron Jones RB | MIN
Packers' Aaron Jones: Injures knee Saturday
Jones is questionable to return to Saturday's game versus the Vikings due to a knee injury.
Jones' last touch before the announcement occurred on a six-yard run on the final play of the first quarter. If he's unable to reenter the contest, he'll finish with three carries for 13 yards. Expect Jamaal Williams to receive nearly all the running back reps in the meantime.
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LeShun Daniels RB | NE
Redskins' LeShun Daniels: Hits injured reserve
The Redskins placed Daniels (hand) on injured reserve Saturday.
Daniels fractured his hand at practice Thursday and was lost for the season. The 22-year-old is the fifth Washington running back to land on injured reserve this season. The Redskins signed Kenny Hilliard to the 53-man roster to provide additional depth out of the backfield.
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Cordarrelle Patterson RB | PIT
Raiders' Cordarrelle Patterson: Good to go this week
Patterson (hip) was not assigned an injury designation for Monday's game against the Eagles after being listed as a full practice participant Saturday.
It looks like there's a pretty solid chance that fellow wideout Amari Cooper (ankle) will return to action in Week 16, which could limit Patterson's opportunities in the Oakland offense Monday. Alternatively, if Cooper ends up being a surprise scratch in advance of the contest, Patterson could serve as a decent last-minute replacement.
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Terrance West RB | BAL
Ravens' Terrance West: Back in the mix Saturday
West is active for Saturday's game against the Colts, Jeff Zrebiec of The Baltimore Sun reports.
West, who was last active back on Oct. 8, adds depth to the team's Week 16 backfield, but we wouldn't expect him to make a big fantasy splash Saturday, with Alex Collins, Danny Woodhead and Javorius Allen also in the mix.
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Mike Gillislee RB | NE
Patriots' Mike Gillislee: In line to return to mix
With Rex Burkhead (knee) out Sunday against the Bills, Gillislee is on track to re-enter the Patriots' backfield mix in Week 16, ESPN's Mike Reiss reports.
There's always an element of risk in rolling with a player who has not played for some time, in Gillislee's case since Oct. 29, but other than the running back feeling under the weather in Week 14, he's been a healthy scratch since then so he'll bring fresh legs to the table in Week 16. All four of Gillislee's TDs this season arrived in the Patriots' first two games, but it's not hard to imagine him seeing some goal-line opportunities in his anticipated return to action Sunday against his former team. Gillislee is thus in line to work in tandem with Dion Lewis, who has emerged as the team's lead back, as well as change-of-pace option James White (ankle), health-permitting.
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Brandon Bolden RB | LV
Patriots' Brandon Bolden: Questionable for Week 16
Bolden is listed as questionable for Sunday's game against the Bills with a groin injury.
Bolden was a limited participant in practice this week to earn the questionable tag. The 27-year-old has not been a factor in the Patriots' backfield this season and should continue to serve his role on special teams if able to suit up Sunday.
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Samaje Perine RB | CIN
Redskins' Samaje Perine: Thinks he'll play
Perine (groin) said he'll be fine for Sunday's game against the Broncos, while Redskins head coach Jay Gruden wasn't so sure, Matthew Paras of The Washington Times reports.
Gruden expects to have a better idea by Saturday, perhaps hoping to see how Perine responds to a day of rest. The rookie tweaked his groin during Thursday's practice and was held out Friday, leading to a 'questionable' designation on the final injury report. With LeShun Daniels (hand) also injured Thursday and already ruled out for the season, Washington promoted Dare Ogunbowale from the practice squad Friday afternoon. Kapri Bibbs likely would handle a large workload if Perine were to miss the game, with Ogunbowale serving as the No. 2 back. Gruden also mentioned that Perine might be limited even if he's active, in which case Bibbs could draw the start.