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Chase Edmonds RB | WAS
Cardinals' Chase Edmonds: Out another week
Edmonds (hamstring) has been ruled out for Sunday's game in Tampa Bay, Josh Weinfuss of ESPN.com reports.
Edmonds was never expected to play and still hasn't returned to practice. It's unclear if he'll be a significant part of the backfield even after he gets healthy, considering the Cardinals also have David Johnson and Kenyan Drake. The team faces the 49ers in Week 11, followed by a bye in Week 12.
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James Conner RB | ARI
Steelers' James Conner: Out of commission Sunday
Conner (shoulder) has been ruled out for Sunday's game versus the Rams, Teresa Varley of the Steelers' official site reports.
Unable to practice due to the AC joint injury in his left shoulder, Conner will miss his second game in a row as a result. With Benny Snell (knee) also sidelined, the Steelers' backfield will be powered by Jaylen Samuels and Trey Edmunds this weekend.
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Christian McCaffrey RB | SF
Panthers' Christian McCaffrey: Good to go
McCaffrey (knee) doesn't have a designation on the Panthers' final injury report for Sunday's game in Green Bay.
McCaffrey closed out the week with back-to-back limited practices, noting afterward that he's feeling great and will be ready for Sunday's game. With the Panthers clawing for a playoff spot, the star running back should see usual workload in game No. 9 of what's shaping up as a historically productive fantasy season. With 246.4 PPR points, McCaffrey is on pace to top LaDainian Tomlinson's record of 481.1 from 2006.
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Christian McCaffrey RB | SF
Panthers' Christian McCaffrey: Feeling ready for Sunday
McCaffrey (knee) said he feels great and will be fine for Sunday's game in Green Bay, Joe Person of The Athletic reports.
McCaffrey was held out of practice Wednesday before participating in a limited fashion Thursday. It isn't clear if he'll have a designation on the final injury report, but he doesn't sound concerned about his knee.
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Austin Ekeler RB | WAS
Chargers' Austin Ekeler: Gets in end zone through air
Ekeler rushed just six times for 19 yards and secured both of his targets for 29 yards and a touchdown in the Chargers' 26-24 loss to the Raiders on Thursday.
As his final numbers indicate, Ekeler was held in check on the ground after a strong 12-carry, 70-yard performance versus the Packers just four days prior. However, the versatile back was able to notch a receiving touchdown for the third time in the last four games by snaring a fourth-quarter scoring toss from Philip Rivers, a catch that also helped him extend his season-long streak of multiple receptions to 10 contests. Ekeler will look to up his overall production when the Chargers face off with the Chiefs in a Monday night Week 11 AFC West showdown Nov. 18.
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Josh Jacobs RB | GB
Raiders' Josh Jacobs: Over 100 total yards in win
Jacobs rushed 16 times for 71 yards and a touchdown and secured three of five targets for 30 yards in the Raiders' 26-24 win over the Chargers on Thursday.
Jacobs had just logged a career-high 28 carries against the Lions four days prior and is nearing the "rookie wall" portion of his first season, so it would have hardly been surprising to see him scuffle for yardage Thursday. However, Jacobs was as effective as usual, and he clinched the narrow victory via an 18-yard touchdown scamper with 1:02 remaining. Jacobs has now has three rushing scores over the last two games, and his 30 receiving yards Thursday were also a career high. He'll look to continue his strong rookie campaign against the vulnerable Bengals defense in Week 11 a week from Sunday.
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Melvin Gordon RB | BAL
Chargers' Melvin Gordon: Keeps building momentum in loss
Gordon rushed 22 times for 108 yards and a touchdown and secured his only target for 25 yards in the Chargers' 26-24 loss to the Raiders on Thursday.
Gordon led all rushers on the night in ground yards, as he continues to ascend back to the high bar he's previously set for himself. The fifth-year back now has three rushing scores over the last two games, and Thursday's 100-yard effort was the first of his truncated campaign. Gordon has also encouragingly logged at least 20 carries in back-to-back games just four days apart, and he'll look to come back even stronger after the extended layoff in a Week 11 Monday night showdown with the Chiefs on Nov. 18.
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Raheem Mostert RB | LV
49ers' Raheem Mostert: Limited by knee injury
Mostert (knee) was a limited practice participant Thursday, Nick Wagoner of ESPN.com reports.
Mostert has played through a knee injury the last three games, but aside from a 41-yard TD run Week 8, he's notched nine rushes for 17 yards (1.9 YPC) and no other scores. Working behind Tevin Coleman and Matt Breida (ankle) doesn't afford Mostert many touches on a weekly basis, especially with a tough Monday night matchup with the Seahawks on tap. First, though, Mostert will look to practice in full Friday and/or Saturday.
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Matt Breida RB | SF
49ers' Matt Breida: Limited to begin Week 10 prep
Breida (ankle) was limited at practice Thursday, Nick Wagoner of ESPN.com reports.
Breida logged a similar number of reps as fullback Kyle Juszczyk (knee) and tackles Joe Staley (fibula) and Mike McGlinchey (knee), a trio that will boost the rushing attack if any of them return to action Monday against the Seahawks. For much of the last two seasons, Breida has played through injuries, so he's a good bet to be available again Week 10. In the end, though, Saturday's injury report will reveal his odds to suit up.
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Alvin Kamara RB | NO
Saints' Alvin Kamara: Back to full health
Kamara (knee/ankle) practiced fully Thursday.
Shortly after Kamara told Amie Just of The New Orleans Times-Picayune that he's "ready to play" Sunday against the Falcons, the Saints revealed he upgraded from limited participation Wednesday to all activity one day later. With his knee and ankle injuries in the rearview mirror, Kamara can turn his focus to an Atlanta defense that has allowed 128.9 yards from scrimmage per game and nine touchdowns to running backs in eight contests this season.