NFL Player News

Mostert (knee) is listed as questionable for Monday's game against the Seahawks, Nick Wagoner of ESPN.com reports.

The reserve running back could have a chance to suit up against the Seahawks, although it's unlikely he'll have a dramatic impact with both Tevin Coleman and Matt Breida (ankle) healthy heading into the prime-time matchup.

Mostert (knee) remained limited Friday at practice, Matt Maiocco of NBC Sports Bay Area reports.

Mostert played through the same injury last week, getting just one carry in a 28-25 win over the Cardinals. His status won't have much impact on the 49ers' game plan unless Matt Breida's ankle injury turns out to be more serious than it currently appears to be.

Breida (ankle) remained limited Friday at practice, Matt Maiocco of NBC Sports Bay Area reports.

Back-to-back limited practices would seemingly put Breida on track to play in Monday's divisional battle with the Seahawks. He has a well-established history of playing through injuries, often at a high level. The 49ers' already-potent rushing attack may get a nice boost this week, with LT Joe Staley (leg), RT Mike McGlinchey (knee) and FB Kyle Juszczyk (knee) all hoping to return from injuries.

Coach Sean Payton hinted that Murray will retain a significant role even with Alvin Kamara now healthy, ESPN.com's Mike Triplett reports. "Week 1 [of] Alvin coming back. We'll be smart," said Payton. "And the good news is the way [Murray] played and the way Alvin's played, we feel like we're real good at that position.

Murray averaged just 4.8 carries and 1.4 targets per game through the first six weeks of the season, but he should see more work Sunday against Atlanta, with Kamara in his first game back from an ankle injury and the Saints heavily favored to win. Murray made an excellent case for continued involvement when Kamara missed Weeks 7 and 8, piling up 307 scrimmage yards and four touchdowns. Kamara said he doesn't mind sharing some more work with Murray moving forward.

Edmonds (hamstring) has been ruled out for Sunday's game in Tampa Bay, Josh Weinfuss of ESPN.com reports.

Edmonds was never expected to play and still hasn't returned to practice. It's unclear if he'll be a significant part of the backfield even after he gets healthy, considering the Cardinals also have David Johnson and Kenyan Drake. The team faces the 49ers in Week 11, followed by a bye in Week 12.

Conner (shoulder) has been ruled out for Sunday's game versus the Rams, Teresa Varley of the Steelers' official site reports.

Unable to practice due to the AC joint injury in his left shoulder, Conner will miss his second game in a row as a result. With Benny Snell (knee) also sidelined, the Steelers' backfield will be powered by Jaylen Samuels and Trey Edmunds this weekend.

McCaffrey (knee) doesn't have a designation on the Panthers' final injury report for Sunday's game in Green Bay.

McCaffrey closed out the week with back-to-back limited practices, noting afterward that he's feeling great and will be ready for Sunday's game. With the Panthers clawing for a playoff spot, the star running back should see usual workload in game No. 9 of what's shaping up as a historically productive fantasy season. With 246.4 PPR points, McCaffrey is on pace to top LaDainian Tomlinson's record of 481.1 from 2006.

McCaffrey (knee) said he feels great and will be fine for Sunday's game in Green Bay, Joe Person of The Athletic reports.

McCaffrey was held out of practice Wednesday before participating in a limited fashion Thursday. It isn't clear if he'll have a designation on the final injury report, but he doesn't sound concerned about his knee.

Ekeler rushed just six times for 19 yards and secured both of his targets for 29 yards and a touchdown in the Chargers' 26-24 loss to the Raiders on Thursday.

As his final numbers indicate, Ekeler was held in check on the ground after a strong 12-carry, 70-yard performance versus the Packers just four days prior. However, the versatile back was able to notch a receiving touchdown for the third time in the last four games by snaring a fourth-quarter scoring toss from Philip Rivers, a catch that also helped him extend his season-long streak of multiple receptions to 10 contests. Ekeler will look to up his overall production when the Chargers face off with the Chiefs in a Monday night Week 11 AFC West showdown Nov. 18.

Jacobs rushed 16 times for 71 yards and a touchdown and secured three of five targets for 30 yards in the Raiders' 26-24 win over the Chargers on Thursday.

Jacobs had just logged a career-high 28 carries against the Lions four days prior and is nearing the "rookie wall" portion of his first season, so it would have hardly been surprising to see him scuffle for yardage Thursday. However, Jacobs was as effective as usual, and he clinched the narrow victory via an 18-yard touchdown scamper with 1:02 remaining. Jacobs has now has three rushing scores over the last two games, and his 30 receiving yards Thursday were also a career high. He'll look to continue his strong rookie campaign against the vulnerable Bengals defense in Week 11 a week from Sunday.