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Boston Scott RB | PIT
Eagles' Boston Scott: Won't suit up Sunday
Scott (ribs) has been ruled out for Sunday's game against the Jaguars, Zach Berman of The Athletic reports.
After missing all three practices this week due to a rib injury, Scott unsurprisingly won't be available to Philly's offense Week 4. While Miles Sanders has been the team's unquestioned No. 1 running back this season, the second and third options have received snaps and touches. Kenneth Gainwell figures to remain the No. 2 back on Sunday, with Trey Sermon active for the first time as an Eagle.
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Melvin Gordon RB | BAL
Broncos' Melvin Gordon: Set to play Sunday
Gordon (neck) doesn't have a designation for Sunday's game in Las Vegas.
Gordon operated under some practice limitations Wednesday and Thursday, but after going through all drills to end Week 4 prep, he's clear for Sunday. On the season, he's been well behind backfield mate Javonte Williams in both snap share (55.3 to 37.2 percent) and touches (52-42), but Gordon at least has visited the end zone one time through three games (Williams has no TDs).
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D'Andre Swift RB | CHI
Lions' D'Andre Swift: Officially ruled out
Swift (shoulder) has been ruled out for Sunday's game against Seattle, Tim Twentyman of the Lions' official site reports.
Swift didn't practice at all this week, and reports suggest he could be held out through the Lions' Week 6 bye. The team hasn't commented on expectations beyond the current week, in which Jamaal Williams will lead the team's backfield against a weak Seattle defense. Craig Reynolds figures to get some carries off the bench, with Justin Jackson potentially having a role as well, but Williams becomes a top-20 play at RB with Swift out of the picture versus such a vulnerable defense.
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David Montgomery RB | HOU
Bears' David Montgomery: Out this week
Montgomery (ankle/knee) has been ruled out for Sunday's game against the Giants.
Montgomery hasn't practiced since his early exit from a Week 3 win over Houston. His departure set up a career-best showing from Khalil Herbert, who is inferior to Montgomery as a blocker and receiver but arguably superior as a pure runner. Trestan Ebner took over the backup role after Montgomery's departure last week, while Darrynton Evans could be called up from the practice squad before Sunday. Herbert figures to start and get the bulk of carries.
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James Conner RB | ARI
Cardinals' James Conner: Ready for Week 4
Conner (knee) doesn't have a designation for Sunday's game at Carolina, Josh Weinfuss of ESPN.com reports.
After opening Week 4 prep with back-to-back limited sessions due to a knee injury, Conner handled every practice rep Friday, paving the way for him to lead the Cardinals backfield yet again this weekend. He's found the going tough through three games this season, mustering 90 yards and a touchdown on 30 carries and recording 10 catches (on 15 targets) for 73 yards.
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Cordarrelle Patterson RB | PIT
Falcons' Cordarrelle Patterson: Technically listed as questionable
Patterson (knee) is listed as questionable for Sunday's game against the Browns after returning to practice Friday, Adam Schefter of ESPN reports.
Patterson was held out Wednesday and Thursday, with the Falcons listing it as "resting player/ knee." That suggests his knee injury isn't serious, as does his return to practice Friday in a limited capacity, according to Tori McElhanney of the team's official site, but the Falcons nonetheless are giving him a designation ahead of a 1:00 p.m. ET kickoff Sunday. Fantasy managers probably will want to check back after inactives are released at 11:30 a.m., even though Patterson is unlikely to be on Atlanta's list. He should be started in most formats if active, as the two best rushing totals of his career (141 and 120 yards) have occurred this season, and he's averaging 16.3 carries per game.
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Ronald Jones RB | DAL
Chiefs' Ronald Jones: Returns to practice Friday
Jones (illness) participated in Friday's practice, Herbie Teope of The Kansas City Star reports.
The extent of Jones' participation remains unclear, but it's encouraging to see him back after he was sidelined Thursday due to an illness. Regardless, Jones finds himself firmly behind Clyde Edwards-Helaire, Isiah Pacheco and Jerick McKinnon and has yet to be active for a game through the first three weeks of the season.
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Dalvin Cook RB | DAL
Vikings' Dalvin Cook: Off injury report entirely
Cook wasn't listed on Minnesota's injury report Friday and will play Sunday versus the Saints, Chris Tomasson of the St. Paul Pioneer Press reports.
Cook returned to a full practice Thursday, and he won't be required to miss any time despite suffering a dislocated shoulder Week 3. The veteran running back isn't unfamiliar with such injuries or playing with a harness to protect his shoulder, and he's previously displayed an ability to do so without requiring a lessened workload. In any case, fantasy managers can safely consider Cook on track for his usual top running back role Sunday versus New Orleans in London.
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D'Andre Swift RB | CHI
Lions' D'Andre Swift: Not expected for Week 4
Coach Dan Campbell said Friday that Swift (shoulder) is "probably out" for Sunday's game against the Seahawks, Jeff Risdon of USA Today reports.
The Lions haven't yet given Swift an official injury designation for Week 4, but it sounds like Campbell considers the third-year pro 'doubtful' for Sunday's contest against Seattle. That would pave the way for Jamaal Williams and Craig Reynolds to lead Detroit's backfield while Swift works to potentially return Week 5 at New England. With Amon-Ra St. Brown (ankle) already ruled out against the Seahawks, the Lions offense could be without arguably its top two playmakers.