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Ronald Jones RB | DAL
Chiefs' Ronald Jones: Inactive again
Jones is inactive for Sunday's game against the Bills.
Jones remains the odd man out in Kansas City's backfield for now. Clyde Edwards-Helaire, Isiah Pacheco and Jerick McKinnon are slated to handle the team's Week 6 RB duties versus Buffalo.
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Keaontay Ingram RB | KC
Cardinals' Keaontay Ingram: Making pro debut Sunday
Ingram is listed as active Sunday at Seattle, Darren Urban of the Cardinals' official site reports.
With James Conner (ribs) and Darrel Williams (knee) sidelined, Ingram, a 2022 sixth-round pick, will be suiting up for the first time in his career. Eno Benjamin is expected to be Arizona's lead runner Week 6, but Ingram should get his share of touches as well considering coach Kliff Kingsbury's penchant for getting multiple running backs involved on a weekly basis. Ingram also has to contend with the elevated Corey Clement behind Benjamin, so it's unclear how much work the rookie can expect in his pro debut.
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Christian McCaffrey RB | SF
Panthers' Christian McCaffrey: Team listening to trade offers
The Panthers are listening to trade pitches on McCaffrey, but Carolina has been adamant about holding on to the running back past the Nov. 1 deadline if it isn't offered a high draft pick or multiple draft picks in return, Adam Schefter of ESPN reports.
Sitting at 1-4 heading into Sunday's game against the Rams and having recently fired head coach Matt Rhule, the Panthers no longer profile as playoff contenders for 2022, but that doesn't necessarily mean that the team will embrace a fire sale of its top players. According to Schefter, the Panthers have already rebuffed at least two teams' inquiries into trading for McCaffrey within the past week, and it looks as though a significant compensation package may be needed to pry the 26-year-old tailback away from Carolina. The Panthers at least made facilitating a potential trade for McCaffrey easier earlier this offseason, when his base salary was lowered to $1.04 million, a figure that should fit under any team's cap without much difficulty.
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Demetric Felton RB | WAS
Browns' Demetric Felton: Will not play Sunday
Felton (coach's decision) is inactive Sunday against the Patriots, Mary Kay Cabot of The Cleveland Plain Dealer reports.
Felton was also inactive last Sunday, and it appears he has fallen behind Chester Rogers on the punt returner depth chart. He'll work to earn a chance to be active in Week 7 against the Ravens.
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Rhamondre Stevenson RB | NE
Patriots' Rhamondre Stevenson: Should be busy Sunday
With Damien Harris (hamstring) inactive, Stevenson is in line to lead the Patriots' rushing corps Sunday against the Browns, Evan Lazar of the team's official site reports.
Rookies Pierre Strong and Kevin Harris are available to handle complementary work, but look for Stevenson to log a heavy workload in Harris' absence Sunday. With Bailey Zappe making his second straight start at QB, Stevenson figures to be a focal point of the Patriots offense versus Cleveland, a context that boosts his Week 6 fantasy upside.
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Myles Gaskin RB | SEA
Dolphins' Myles Gaskin: Healthy scratch Week 6
Gaskin (coach's decision) is a healthy inactive for Sunday's game against the Vikings.
Even though he gained 33 yards on seven touches (four carries, three receptions) and played more snaps (13) than No. 2 back Chase Edmonds (nine) in the 40-17 loss to the Jets in Week 5, Gaskin will find himself in street clothes Sunday. The return of Salvon Ahmed from a one-game absence due to a back injury looks like it might have been enough to bump Gaskin to the inactive list. Gaskin is ahead of Ahmed in the pecking order out of the backfield, but Ahmed's ability to contribute on special teams was deemed more useful than having Gaskin on hand as extra depth behind starter Raheem Mostert.
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Raheem Mostert RB | LV
Dolphins' Raheem Mostert: Suiting up Sunday
Mostert (knee) is active for Sunday's game against the Vikings.
Mostert was tending to the knee injury in the aftermath of carrying 18 times for a season-high 113 yards and a touchdown in the Dolphins' Week 5 loss to the Jets, but his ability to practice on a limited basis Thursday and Friday looks like it was enough to convince Miami to keep him active for Week 6. At this point, Mostert appears to have asserted himself as the top option out of the Miami backfield, but he could struggle to replicate the 18 carries he saw a week ago if the underdog Dolphins find themselves trailing early against Minnesota. Third-string quarterback Skylar Thompson will be making his first career start Sunday, and his presence under center could make it difficult for the Dolphins to string together long drives.
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Alexander Mattison RB | MIA
Vikings' Alexander Mattison: Officially available for Week 6
Mattison is active for Sunday's matchup against the Dolphins.
Mattison picked up a shoulder injury during the Vikings' Week 5 win over the Bears and was limited at each practice ahead of Week 6, earning him a questionable designation. As expected, the backup running back will be available, but it's unclear how much work he'll get behind Dalvin Cook. Mattison turned a season-high 12 touches into 40 scrimmage yards last week and has totaled 37 touches for 154 yards and two scores across five appearances this year.