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Jamaal Williams RB | NO
Lions' Jamaal Williams: Another rushing touchdown
Williams rushed 18 times for 66 yards with one touchdown and one lost fumble during Thursday's 28-25 loss to the Bills.
Williams continued to handle the lion's share of work out of the backfield and extended his league-leading touchdown total (13) along the way. With Detroit seemingly keen on keeping D'Andre Swift as fresh as possible going forward, Williams should continue to handle a heavy workload down the stretch, though one that may not involve much heavy lifting as a receiver given Swift's proficiency in that area. Up next is a middling Week 13 matchup against a Jaguars defense allowing the eighth-fewest yards per carry (4.2) and the 11th-fewest rushing touchdowns (nine) in 2022.
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Alvin Kamara RB | NO
Saints' Alvin Kamara: DNP due to illness
Kamara was absent from Thursday's session due to an illness, Nick Underhill of NewOrleans.Football reports.
Kamara wasn't spotted at the media-access portion of the Saints' second practice of Week 12, and the reason for the DNP now is known. He doesn't have much time to get past the bug ahead of Sunday's game at San Francisco, but he at least has one more opportunity to participate in drills Friday before the team potentially gives him a designation. With Mark Ingram (knee) back on the field as limited this week, he could be New Orleans' lead runner Sunday if Kamara is at all inhibited.
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Hassan Haskins RB | NE
Titans' Hassan Haskins: Added to injury report
Haskins (hip) was listed as limited on Thursday's estimated injury report, Ben Arthur of FoxSports.com reports.
Haskins was not on the injury report Wednesday, and his late-week addition casts some doubt on his status for Sunday's game against the Bengals. If Haskins is unable to play, the Titans may have to promote Julius Chestnut from the practice squad.
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Aaron Jones RB | MIN
Packers' Aaron Jones: Stays limited Thursday
Jones (shin/glute) was limited at Thursday's practice.
Jones continues to deal with a shin injury, but this week a glute issue also is being listed next to it, inhibiting his reps for a second session in a row. Friday's practice report could clear up his status entering the weekend, but if he's questionable for Sunday's game at Philadelphia, an 8:20 p.m. ET kickoff doesn't provide many places to turn for RB help if he's limited or out. Currently, AJ Dillon is the only other backfield option on the Packers' active roster.
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Chris Evans RB | CIN
Bengals' Chris Evans: Listed as full participant
Evans (knee) was listed as a full participant on Thursday's practice report, Jay Morrison of The Athletic reports.
Evans missed last week's win over the Steelers due to a knee injury and was limited at practice Wednesday, but he appears to be back to full health ahead of Sunday's game in Tennessee. Joe Mixon is in the league's concussion protocol, so it's possible Evans will take on a starting role in Week 12.
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Joe Mixon RB | HOU
Bengals' Joe Mixon: Misses another practice
Mixon (concussion) remained sidelined at practice Thursday.
Following back-to-back missed sessions, Mixon has one more chance to take the practice field ahead of Sunday's game against the Titans. Friday's injury report will reveal whether the running back has a chance to suit up this weekend, but if Mixon is unable to gain clearance to face Tennessee, Samaje Perine would be in line to lead Cincinnati's Week 12 backfield, with Chris Evans and Trayveon Williams also on hand.
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Raheem Mostert RB | LV
Dolphins' Raheem Mostert: Misses another practice
Mostert (knee) didn't practice Thursday, Daniel Oyefusi of the Miami Herald reports.
Back-to-back DNPs cloud Mostert's status for Sunday's game against the Texans, but a return to drills Friday in any capacity would give the running back a chance to suit up this weekend. If Mostert is out or limited, Salvon Ahmed and Myles Gaskin would be candidates to see added backfield work Week 12 behind Jeff Wilson.
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Jaylen Warren RB | PIT
Steelers' Jaylen Warren: Sits out practice Thursday
Warren (hamstring) didn't practice Thursday, Teresa Varley of the Steelers' official site reports.
Warren suffered what coach Mike Tomlin referred to as "not a significant" hamstring injury Week 11 against the Bengals, but at this stage the running back's status for Monday night's game against the Colts is uncertain. He now has two more chances to return to practice ahead of the contest, but if he's unavailable, Benny Snell would be in line to log complementary snaps Week 12 behind top back Najee Harris.
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Gus Edwards RB | LAC
Ravens' Gus Edwards: Listed as full practice participant
Edwards (hamstring/knee) was listed as a full practice participant Thursday, Jamison Hensley of ESPN.com reports
Edwards' return to a full practice listing puts him on track to be back in action Sunday against the Jaguars and reclaim a portion of the Ravens' early down work after missing two games, with Kenyan Drake and Justice Hill also mixing in. In that context, Edwards profiles as a TD-dependent option in Week 12 fantasy lineups given his limited usage in the team's passing game.
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Latavius Murray RB | BUF
Broncos' Latavius Murray: Limited on practice estimate
Murray (wrist) was listed as limited on Thursday's practice estimate.
Murray also was listed as limited Wednesday, so he may need to practice fully Friday in order to avoid an injury designation ahead of Sunday's game against the Panthers. Assuming he's active this weekend, Murray will be in line to lead Denver's Week 12 rushing attack, with Marlon Mack in reserve and the team likely to add further backfield depth via the practice squad.