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JaMycal Hasty RB | NE
Patriots' JaMycal Hasty: Healthy inactive
Hasty (coach's decision) will not play in Sunday's matchup with the Giants.
Hasty will be a healthy scratch in his first game with the Patriots since being claimed off waivers from the Jaguars. This is not surprising, as Rhamondre Stevenson, Ezekiel Elliott and Ty Montgomery are all healthy. Hasty's next chance to suit up will come in one week versus the Chargers.
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Ke'Shawn Vaughn RB | SF
Buccaneers' Ke'Shawn Vaughn: Healthy scratch again
Vaughn (coach's decision) is inactive ahead of Sunday's game against the Colts, Scott Smith of the Buccaneers' official site reports.
The fourth-year running back out of Vanderbilt seems to have been passed by both Chase Edmonds and Sean Tucker on Tampa Bay's depth chart, as he'll be a healthy scratch for the third consecutive game. Vaughn has appeared in six games for the Buccaneers this season, recording 44 total yards on 26 touches.
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Mike Boone RB | MIA
Texans' Mike Boone: Healthy scratch for Week 12
Boone (coach's decision) is a healthy inactive for Sunday's game against the Jaguars.
Dameon Pierce (ankle) is active after missing the Texans' last three games, leaving no room in the backfield for Boone. Pierce and Devin Singletary -- the latter of whom served as Houston's lead back during Pierce's absence -- are expected to share most of the snaps on offense, while Dare Ogunbowale is active as the Texans' No. 3 back but is likely to see most of his playing time on special teams.
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Chase Brown RB | CIN
Bengals' Chase Brown: Back in action Sunday
Brown (hamstring) is active for Sunday's game against the Steelers, Charlie Goldsmith of The Cincinnati Enquirer reports.
Brown was activated from IR on Saturday, and he'll be in uniform for the first time since Week 6. In five games prior to landing in IR, the 2023 fifth-rounder carried just twice for six yards and caught three passes for seven yards, so until the rookie carves out a steady role behind top back Joe Mixon in a backfield that also includes Trayveon Williams, he'll be off the fantasy radar.
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Eric Gray RB | CLE
Giants' Eric Gray: Ready for return
Gray (calf) is active Sunday against the Patriots, Dan Salomone of the Giants' official site reports.
Gray was able to log back-to-back full practices after being designated to return from IR on Wednesday and he was added to the 53-man roster Saturday. The rookie running back should operate as the team's No. 3 option at the position, behind starter Saquon Barkley and backup Matt Breida.
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Devin Singletary RB | NYG
Texans' Devin Singletary: Rejoined in backfield by Pierce
Texans offensive coordinator Bobby Slowik suggested earlier in the week that Singletary will likely "share the load" Sunday against the Jaguars with Dameon Pierce (ankle), who is active after missing Houston's last three games, Jonathan M. Alexander of the Houston Chronicle reports.
Pierce served as Houston's starting running back for the first seven games of the season but was one of the NFL's least-efficient runners, averaging a paltry 3.0 yards on 109 carries. While Pierce has been out the last three games with a high-ankle sprain, Singletary has given life to Houston's ground attack, taking 65 carries for 288 yards (4.4 average) and two touchdowns while adding five catches for 17 yards. Though Pierce isn't expected to face any restrictions Sunday after practicing fully Wednesday through Friday, he could have to settle for the No. 2 role out of the backfield or work in a timeshare with Singletary. Even if that's the case, Singletary will likely lose out on some touches and snaps with Pierce back in the fold, making Singletary less appealing of a fantasy play than he had been in the past three weeks.
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Anthony McFarland RB | MIA
Steelers' Anthony McFarland: Healthy scratch against Cincinnati
McFarland (coach's decision) is inactive for Sunday's game against the Bengals, Mike DeFabo of The Athletic reports.
McFarland has served as Pittsburgh's primary kick returner when healthy this season. However, he was surpassed by Godwin Igwebuike for the role in Week 11 and that has seemingly carried forward into Week 12.
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Dameon Pierce RB | PHI
Texans' Dameon Pierce: Returns from three-game absence
Pierce (ankle) is active for Sunday's game against the Jaguars.
Pierce missed the Texans' last three games due to a high-ankle sprain and was listed as questionable heading into Sunday, but there was no real mystery with regard to his Week 12 status after he put in full practices Wednesday through Friday. Whether Pierce reclaims the lead role out of the backfield he held through the Texans' first seven games of the season is less certain, however, especially after Devin Singletary accounted for 305 total yards and two touchdowns on 70 touches (65 carries, five receptions) over the past three games while proving to be far more efficient than Pierce, who is averaging just 3.0 yards per carry on the season. Per Jonathan M. Alexander of the Houston Chronicle, offensive coordinator Bobby Slowik said Wednesday that he believes in "sharing the load" between Pierce and Singletary, but it's unclear what exactly the breakdown of work between the two backs might look like.
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Rachaad White RB | WAS
Buccaneers' Rachaad White: Playing in Week 12
White (knee) is active for Sunday's game in Indianapolis, Scott Smith of the Buccaneers' official site reports.
The Buccaneers tacked on White to their practice report Saturday due to a knee injury, which left him questionable for Week 12 action. Adam Schefter of ESPN reported Saturday evening that while White's knee locked up on him for a brief spell at Friday's practice, the running back was expected to play Sunday. Indeed, that has come to fruition, and White now will be taking on a Colts defense that has given up the fifth-most touchdowns (12) to opposing running backs in 10 games this season.