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2:29Cleveland Browns Two-Minute Practice Check-In: 12/10/25
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1:15Should Browns Stick With Shedeur Sanders?
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3:02Week 15 NFL Game Picks: Browns at Bears
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1:54Where Was Sanders On 2-Point Attempt?
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1:07Rookie QB Showdown: Ward Gets Win But Shedeur Shines
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0:47Geico Feel Good Moment: Myles Garrett's 20th Sack
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2:25Two-Minute Post-Game Check-In: Titans 31, Browns 29
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2:17Week 14 Highlights: Titans at Browns
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2:11Cleveland Browns Two-Minute Practice Check-In: 12/5/25
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2:34Cleveland Browns Two-Minute Practice Check-In: 12/4/25
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2:39Cleveland Browns Two-Minute Practice Check-In: 12/3/25
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2:07Browns Myles Garrett Chasing NFL Sack Record
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1:32Browns Open Their Practice Window For Deshaun Watson
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6:13Browns Opening Their Practice Window For Deshaun Watson
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1:30Ryan Wilson's Top 3 First-Round QB Predictions
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1:52Week 14 NFL Picks: Titans at Browns
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1:24Will Shedeur Sanders Be The Browns QB Next Season?
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2:19Cleveland Browns Post-Game 2-Minute Check-In: 11/30/25
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1:25San Francisco 49ers Take Another Step Towards Playoff Football
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1:59Rough Day For Shedeur Sanders and the Browns vs the 49ers
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2025 Defensive
| STATS |
CMB
Total Tackles
|
SCK
Sacks
|
FUM
Forced Fumbles
|
INT
Interceptions
|
TD
Interceptions Returned For Touchdown
|
|---|---|---|---|---|---|
| Regular Season | 29 | 2.0 | 1 | 0 | 0 |
Top Isaiah McGuire News
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Browns' Isaiah McGuire: Cleared to play vs. Tennessee
McGuire (knee) is active for Sunday's game against the Titans.
McGuire had his practice reps limited during Week 14 prep due to a knee injury, but the third-year defensive end has been cleared to play Sunday after going through pregame warmups. He has accumulated 29 tackles (17 solo), including 2.0 sacks, and one forced fumble through 12 regular-season games.
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Browns' Isaiah McGuire: Questionable with knee issue
McGuire (knee) is listed as questionable for Sunday's game against the Titans, Chris Easterling of the Akron Beacon Journal reports.
McGuire was a non-participant in Wednesday's practice before stringing consecutive limited sessions together to end the week. The consistent participation means the defensive end is likely trending towards suiting up for Sunday. If the 24-year-old is unable to go, Cameron Thomas would be in line to see more rotational snaps at defensive end.
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Browns' Isaiah McGuire: Joins sack party in Week 12 win
McGuire posted seven tackles (four solo), including 1.0 sacks, and two QB hits during the Browns' 24-10 win over the Raiders on Monday.
McGuire got to Geno Smith twice during Sunday's win, with the former splitting sacks with Mike Hall and Cameron Thomas in the third and fourth quarter, respectively. McGuire's seven stops were a season high, and the third-year defensive end is up to 28 tackles (17 solo), including 2.0 sacks, and one forced fumble through 11 regular-season games.
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Browns' Isaiah McGuire: Returns to practice Thursday
McGuire (illness) logged a full practice session Thursday, Daniel Oyefusi of ESPN.com reports.
McGuire missed Wednesday's practice due to an illness, but he was back and able to participate in full one day later. As such, the third-year defensive end should be good to go against the Jets on Sunday.
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Browns' Isaiah McGuire: Under the weather
McGuire did not participate in Wednesday's practice due to an illness, Mary Kay Cabot of The Cleveland Plain Dealer reports.
McGuire is under the weather to start Week 10 prep, but he'll have two more opportunities to return to practice ahead of Sunday's game against the Jets. The third-year defensive end has logged 16 tackles (10 solo), including 1.0 sacks, and one forced fumble through eight regular-season games.
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Browns' Isaiah McGuire: Steps up in Year 2
McGuire racked up 36 tackles (18 solo), including 2.5 sacks, plus three forced fumbles across 16 regular-season appearances with the Browns in 2024.
McGuire ramped up his involvement on defense Year 2, managing to close out the campaign as a clear starter. The 2023 fourth-round pick suited up for just four games as a rookie, but he's now demonstrated a legitimate ability to contribute on defense. He'll spend the offseason looking to further his development in Cleveland's scheme.
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Player Bio
| HT/WT: 6-4, 268 lbs |
| Birthplace: Tulsa, OK |
| Age: 24 |
| School: Missouri |
| Experience: 3 |