Lopez (toe) has been ruled out for the remainder of Sunday's matchup with the Seahawks, Darren Urban of the Cardinals' official site reports.
Lopez sustained a toe injury late in the first half, and he will now be forced to miss the rest of Week 9. In his absence, Andrew Billings is a top candidate to continue to see added snaps at defensive tackle against Seattle.
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Cardinals' Roy Lopez: Questionable to return
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Lopez (toe) is questionable to return to Arizona's matchup versus the Seahawks on Sunday.
Lopez suffered a toe injury in the first half, leaving his status for the rest of the game up in the air. If the 2021 sixth-round pick ends up being unable to return, Andrew Billings and L.J. Collier could see an uptick in playing time for the remainder of the matchup.
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Cardinals' Max Melton: Set for Sunday
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Melton (knee) is active for Sunday's game against the Seahawks.
Melton logged consecutive limited practices to end Week 9 prep. The cornerback appears to have overcome his knee injury in time to play in Sunday's contest, leaving Kalen King to remain in a reserve role for Week 9.
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Cardinals' Walter Nolen: Active for Week 9
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Nolen (ankle) is active for Sunday's game against the Seahawks.
Nolen's trio of limited practices during Week 9 prep proves enough to allow the defensive tackle to suit up for Sunday's game. The 23-year-old accumulated 14 tackles (five solo), including 1.0 sacks, in the 2026 regular season before missing consecutive contests with an ankle injury.
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Cardinals' Walter Nolen: Could return Sunday
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Nolen (ankle) is questionable for Sunday's Week 9 tilt against the Seahawks, Josh Weinfuss of ESPN.com reports.
An ankle injury caused Nolen to miss Arizona's past two contests, but he was able to log a trio of limited practices this week. That gives him at least a chance of suiting up Sunday in Seattle. Should Nolen need to sit out again, though, L.J. Collier could soak up most of his defensive snaps.
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Cardinals' Max Melton: May miss Week 9
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Melton (knee) is questionable to play against Seattle on Sunday, Josh Weinfuss of ESPN.com reports.
Melton missed Week 7 versus Denver due to a knee issue but was able to return last Sunday against Dallas. However, the injury is still a concern, and the third-year cornerback was limited in practice both Thursday and Friday this week. If he can't play Week 9, Kalen King may log a start.
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Cardinals' Max Melton: Active versus Dallas
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Melton (knee) is active for Sunday's game against the Cowboys, Darren Urban of the team's official site reports.
Melton was inactive for the Week 7 meeting with the Broncos. While he was listed as questionable for Sunday's game against Dallas after logging three limited practice sessions during the week, he has since been cleared to suit up, likely resulting in fewer snaps for Kalen King.
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Cardinals' Andrew Wingard: Returning in Week 8
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Wingard (knee) is active for Sunday's game versus the Cowboys, Darren Urban of the team's official site reports.
Wingard has been battling a bone bruise in his knee. While it didn't result in a stint on injured reserve, it kept him off the field for Arizona's last three contests. Now that Wingard is available to return in Week 8, it will likely mean fewer snaps for Dadrion Taylor-Demerson.
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Cardinals' Max Melton: Questionable for Week 8
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Melton (knee) is questionable for Sunday's game against the Cowboys, Josh Weinfuss of ESPN.com reports.
Melton put together three-straight limited practices while working through a knee injury that prevented him from playing against the Broncos in Week 7. Kalen King would be in line for more snaps in the secondary if Melton is not cleared by medical staff to play Sunday.
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Cardinals' Andrew Wingard: Tagged as questionable for Week 8
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Wingard (knee) is questionable for Sunday's game against Dallas, Josh Weinfuss of ESPN.com reports.
Wingard has a chance to return from a three-game absence due to a knee injury. His practice reps were limited during Week 8 prep, and if he's not cleared to play, then Dadrion Taylor-Demerson would likely start alongside Budda Baker at safety.
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Cardinals' Mack Wilson: Cleared to play against Dallas
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Wilson (knee) does not have an injury designation for Sunday's game against the Cowboys, Josh Weinfuss of ESPN.com reports.
Wilson's practice reps were limited due to a knee injury, but the veteran linebacker's full practice Friday was enough for him to fade an injury tag for Sunday's road game. The 2019 fifth-rounder has 47 tackles (20 solo), one pass defense and one forced fumble through seven regular-season games.
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Cardinals' Walter Nolen: Won't play against Dallas
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Nolen (ankle) has been ruled out for Sunday's game against the Cowboys, Theo Mackie of The Arizona Republic reports.
Nolen will end up missing a second consecutive game due to an ankle injury that he sustained in Week 6 against the Rams. L.J. Collier and Andrew Billings should both see an uptick in snaps on the defensive line in the absence of Nolen, whose next chance to play is Week 9 against the Seahawks on Sunday, Nov. 8.
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Cardinals' Mack Wilson: Limited practice participant Thursday
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Wilson (knee) was limited in Thursday's practice, Theo Mackie of The Arizona Republic reports.
Wilson didn't practice Wednesday, but he was out there Thursday in a limited capacity. He'll likely need another limited session Friday to avoid an injury designation ahead of the Week 8 meeting with the Cowboys.
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Cardinals' Andrew Wingard: Manages limited practice Wednesday
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Wingard (knee) was a limited participant at practice Wednesday, Darren Urban of the Cardinals' official site reports.
Wingard has been sidelined for the Cardinals' past three games due to a bone bruise in his knee he sustained back in Week 4 against the Giants, and now his availability for Week 8 is in question. If he can upgrade to full participation at practice Thursday or Friday, there's a good chance he'll suit up Sunday at Dallas.
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Cardinals' Mack Wilson: Misses practice Wednesday
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Wilson (knee) did not participate at practice Wednesday, Darren Urban of the Cardinals' official site reports.
Wilson's absence Wednesday was marked not injury related, but there does seem to be a knee issue. His activity at practice Thursday and Friday should offer more insight into whether he's truly in danger of sitting out in Week 8.
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Cardinals' Budda Baker: Only two stops in Week 7 loss
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Baker logged two tackles (one solo) during Sundays' 30-16 loss to Denver.
Baker was cleared to play against the Broncos after nursing a groin injury and an illness during Week 7 prep. He was on the field for 59 of the Cardinals' 61 defensive snaps (96.7 percent), but his two stops were a season low. The veteran safety is up to 44 tackles (25 solo), including a career-best 3.5 sacks, and four pass defenses (including one interception) through seven regular-season games.
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Cardinals' Jack Gibbens: Team-high seven stops vs. Denver
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Gibbens recorded seven tackles (four solo) in a 30-16 loss to the Broncos on Sunday.
Gibbens' 41 defensive snaps were a season low, but the fifth-year linebacker still led the Cardinals in tackles. He's posted at least seven stops in six of seven regular-season games and is up to 49 tackles (21 solo), including 0.5 sacks, and one pass defense in 2026.
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Cardinals' Max Melton: Sidelined for Week 7
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Melton (knee) is inactive for Sunday's game against the Broncos, Darren Urban of the Cardinals' official site reports.
There was optimism that Melton would be cleared to play, but the third-year defensive back will be sidelined by a knee issue and observe Sunday's game from street clothes. Kalen King is in line for more defensive snaps due to the absence of Melton, whose next chance to play is Week 8 against the Cowboys on Sunday, Nov. 1.
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Cardinals' Budda Baker: Cleared to face Denver
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Baker (groin) is active against the Broncos on Sunday, Darren Urban of the Cardinals' official site reports.
Baker has been working through both a groin injury and an illness, but the veteran safety has been given the green light by medical staff to play Sunday. He has 42 tackles (24 solo), including a career-best 3.5 sacks, and four pass defenses (one interception) through six regular-season games.
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Cardinals' Budda Baker: Should play Week 7
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Baker (groin) is listed as questionable but expected to play against the Broncos on Sunday, Ian Rapoport of NFL Network reports.
Baker missed the first two practices of the week due to both an illness and groin injury before logging a limited session Friday. That was enough for him to draw the questionable tag for Week 7, and it appears the veteran safety will suit up against Denver.