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Kenneth Walker III RB | KC
Seahawks' Kenneth Walker: Limited Wednesday
Walker was limited at Wednesday's practice due to a glute injury, John Boyle of the Seahawks' official site reports.
Since the Seahawks' Week 8 bye, Walker has continued to be the 1A in the team's backfield over Zach Charbonnet over the last four contests. Walker has turned 61 touches into 343 yards from scrimmage and one TD during that span, while Charbonnet has notched 42 touches for 211 total yards and two TDs. Walker has a health concern to contend with this week, but he'll have two more chances to get back to full before Seattle potentially tags him with a designation for Sunday's game against the Vikings.
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David Njoku TE | LAC
Browns' David Njoku: Limited at practice Wednesday
Njoku (knee) was limited at practice Wednesday.
Njoku continues to manage a knee issue, but as long as he's able to practice fully by Friday he'll be on track to approach Sunday's game against the 49ers without an injury designation. With just one catch (on two targets) over his last two games, a span in which fellow TE Harold Fannin has combined for six catches on 11 targets, Njoku profiles as a hit-or-miss Week 13 fantasy lineup option.
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Jermaine Burton WR | CIN
Bengals' Jermaine Burton: Won't play on Thanksgiving
Burton (ankle) has been ruled out ahead of Thursday's game against the Ravens.
Burton didn't appear on the injury report until Wednesday, suggesting he suffered the ankle injury during practice. He has yet to be active for a game this season.
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Myles Gaskin RB | SEA
Myles Gaskin: Returning to Seattle
The Seahawks re-signed Gaskin to their practice squad Wednesday, John Boyle of the team's official site reports.
Gaskin will rejoin the team after being cut from the practice squad last week. The 28-year-old has yet to appear in a game this season but could be elevated for Sunday's matchup versus the Vikings, as George Holani (hamstring) is currently listed as doubtful.
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Tatum Bethune LB | SF
49ers' Tatum Bethune: Misses practice Wednesday
Bethune (ankle) was absent from practice Wednesday, Matt Barrows of The Athletic reports.
Bethune was forced to miss the team's Week 12 win over the Panthers due to a right high ankle sprain, and he has now been forced to miss the team's first practice session of the week. The linebacker will have two more chances to return to practice prior to Sunday's matchup with the Browns in Cleveland. If he can't go in Week 13, Curtis Robinson would likely step into a starting role at middle linebacker for a second week in a row.
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Omarion Hampton RB | LAC
Chargers' Omarion Hampton: Back at practice, limited Wednesday
Hampton (ankle) was limited in his return to practice Wednesday, Eric Smith of the Chargers' official site reports.
Hampton, who last saw game action in Week 5 when he sustained a fractured ankle, was designated to return from IR on Tuesday, which has the running back trending in the right direction ahead of Sunday's game against the Raiders. Per Smith, Hampton's Week 13 availability presumably hinges on how he fares this week at practice, but for his part, the 2025 first-rounder is anxious to return to the lineup. "They haven't told me yet, but I'm waiting to find out. Whatever my doc says," Hampton noted Wednesday. "I want to, for sure. But it's whatever the doc says." In any case, in order for Hampton to be available versus Las Vegas, he'd need to be activated from IR by Saturday afternoon.
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Yetur Gross-Matos DE | SF
49ers' Yetur Gross-Matos: Will remain on IR
Head coach Kyle Shanahan relayed Wednesday that the 49ers will not designate Gross-Matos (knee) to return from injured reserve, Matt Maiocco of NBC Sports Bay Area reports.
Gross-Matos missed three games in October before landing on injured reserve Nov. 1 due to a hip injury. This Sunday's game against the Browns will mark his eighth-straight missed game, and with the 49ers on a bye Week 14, his next opportunity to play is Week 15 against the Titans on Sunday, Dec. 14.
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Rylie Mills DT | SEA
Seahawks' Rylie Mills: Designated to return
The Seahawks designated Mills (knee) to return from the reserve/non-football injury list Wednesday, Brady Henderson of ESPN reports.
Mills has been on the NFI list since July but is now one step closer to making his return. The team will now have 21 days to officially activate the rookie fifth-round pick, who will look to make his NFL debut once fully healthy.
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Michael Mayer TE | LV
Raiders' Michael Mayer: Misses practice Wednesday
Mayer (ankle) didn't practice Wednesday.
Mayer exited this past Sunday's loss to the Browns after logging 13 snaps on offense, and the tight end's DNP on Wednesday clouds his Week 13 status. Mayer now has two more chances to practice before the Raiders unveil their final injury designations ahead of Sunday's game against the Chargers.
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Cam Akers RB | SEA
Seahawks' Cam Akers: Signs with Seattle
The Seahawks signed Akers on Wednesday, Brady Henderson of ESPN reports.
Akers is headed to Seattle after being cut from Minnesota's practice squad last week. The 26-year-old carried the ball five times for 19 yards in three appearances with the Vikings. He should serve as the Seahawks' No. 3 running back for Sunday's matchup against his former team, as George Holani is doubtful with a hamstring injury.