NFL Player News

Ferguson (ankle) was expected to return for Sunday's game against Washington, but he's been ruled out after injuring his hamstring during Friday's practice, Cameron DaSilva of USA Today reports.

Ferguson made it back from his ankle injury, only to be sidelined by another concern two days before he was set for a return to game action. The Rams could use him, as they haven't found a second consistent receiving threat alongside Puka Nacua in the absence of Davante Adams (IR - hamstring). Another absence for Ferguson leaves Tyler Higbee as well as Colby Parkinson (ribs, questionable), if available, as the Rams' tight top ends, with Davis Allen and Max Klare providing extra bodies for multi-TE sets.

Lock (right elbow) doesn't have a designation for Sunday's contest against the Cardinals, John Boyle of the Seahawks' official site reports.

Lock logged three consecutive limited sessions this week due to the right elbow injury that has relegated him to inactive status as the emergency third quarterback the last two games. However, with his status now cleared up for Week 9 action, he's set to fill in for Sam Darnold (quadriceps/ribs) for at least one contest. In two previous appearances (one start) in place of Darnold in Weeks 1 and 2, Lock completed 35 of 48 passes (73 percent) for 422 yards, four touchdowns and no interceptions and had two carries for 13 yards. Jalen Milroe will back up Lock on Sunday.

Wilson (rest/ribs) doesn't have a designation for Sunday's contest in Seattle, Josh Weinfuss of ESPN.com reports.

Wilson has worn a yellow non-contact jersey in practice the last two weeks due to two broken ribs -- a situation that contained him to limited sessions. Having said that, he'll continue to play through the concern as he did this past Sunday in Dallas, when he hauled in eight of 15 targets for 111 yards and one touchdown while adding one carry for 17 yards on a 79 percent snap share.

McCaffrey (hamstring) doesn't have a designation for Sunday's game versus the Raiders, Nick Wagoner of ESPN.com reports.

McCaffrey was a limited practice participant Thursday and Friday, which was enough for him to gain clearance to suit up in Week 9. He was hampered by a left hamstring injury during the 49ers' last game in Week 7 in Atlanta, when he handled a season-low 52 percent snap share but still notched 100 yards from scrimmage and a rushing TD on 13 touches.

Evans (Achilles) has been ruled out for Sunday's game against the Raiders, Nick Wagoner of ESPN reports.

GM John Lynch said on KNBR radio Thursday that Evans is unlikely to play in Week 9 due to the right Achilles injury he aggravated in Week 6 against the Commanders, per Matt Maiocco of NBC Sports Bay Area. After not practicing in any capacity Wednesday and Thursday, Evans indeed will miss a second consecutive contest. Fellow WRs Deebo Samuel (hamstring) and Christian Kirk (knee) will join Evans on the sideline Sunday, leaving Jordan Watkins, Brandin Cooks and Jacob Cowing as the only options at the position on the 49ers' active roster. The team also may activate Demarcus Robinson (ankle) from IR on Saturday after he was listed as questionable.

Coleman (shoulder) was a limited practice participant Friday.

Coleman is on the injury report for the first time since Week 4, listed as a limited participant Thursday and Friday due to a shoulder injury. There's been no indication it's serious, so Coleman seems on track to play Monday night at Minnesota. Fellow Bills wideout DJ Moore (shoulder) also is gearing up to play.

Johnson (illness) was a full practice participant Friday.

A quick return after Thursday's absence confirms Johnson isn't dealing with a serious illness. He should be fine for his usual role on passing downs Monday night at Minnesota.

Kirk (knee) will miss Sunday's game against Las Vegas and may need surgery for a meniscus injury, David Lombardi of SFStandard.com reports.

After opening the year on injured reserve with a calf injury, Kirk finally got healthy and played 20 snaps in a Week 7 loss to Atlanta. Other injuries at wide receiver opened up an opportunity, but now it seems Kirk is more likely to go back on IR than make an impact in the coming weeks.

Ferguson (ankle) doesn't have an injury designation for Sunday's game against the Commanders, Adam Caplan of SiriusXM NFL Radio reports.

The tight end is expected to be activated from injured reserve Saturday afternoon and make his return to the lineup Sunday. With Davante Adams (hamstring) out several more weeks, Ferguson has a big opportunity to essentially serve as the Rams' WR2, putting him in the mix as a fantasy starter at tight end.

Samuel (hamstring) has been ruled out for Sunday's game against the Raiders, Nick Wagoner of ESPN.com reports.

Neither Samuel nor Mike Evans (Achilles) made a serious bid to play in San Francisco's first game after a Week 8 bye. Jordan Watkins, Brandin Cooks and Jacob Cowing are the healthy WRs on the active roster, with Demarcus Robinson (ankle) a candidate to come off injured reserve this week or next.