Huff (hamstring) was a limited participant in Wednesday's practice, Cam Inman of The San Jose Mercury News reports.

Huff has missed the 49ers' last two games due to a hamstring strain, but his return to practice Wednesday is a sign that the veteran pass rusher is progressing in his recovery. He could return against the Colts on Sunday, and his availability is key given that Mykel Williams suffered a season-ending torn ACL during the 49ers' Week 9 win over the Giants, further depleting San Francisco's defensive end depth that also has Yetur Gross-Matos (knee), Nick Bosa (knee - ACL) and Tarron Jackson (undisclosed) all on injured reserve.

The Lions placed Mahogany (leg) on injured reserve Wednesday, Allen Park of Michigan Live reports.

Mahogany will be forced to miss at least four weeks after suffering a leg injury in the fourth quarter of the Week 9 loss to the Vikings. The 25-year-old isn't expected to return until December, and in his absence, Kayode Awosika will likely take over as Detroit's starting left guard.

Whittington (back) was a non-participant at practice Wednesday, Adam Caplan of SiriusXM NFL Radio reports.

Whittington popped up on the injury report with an apparent back injury to open the week. The wide receiver failed to garner a target in the team's 34-10 win over the Saints in Week 9, potentially getting hurt during the game. He'll have two more chances to return to practice prior to Sunday's contest against the 49ers.

Winters (knee) was limited in Wednesday's practice, Cam Inman of The San Jose Mercury News reports.

Winters was able to play through a knee injury against the Giants in Week 9, when he played every single defensive snap while recording five tackles (two solo). He'll have two more chances to log a full practice this week, but even if he remains limited, he's likely to be available for Sunday's game against the Colts, barring a setback.

Jobe (concussion) was estimated to be a nonparticipant at Wednesday's walkthrough practice, John Boyle of the Seahawks' official site reports.

Jobe suffered a concussion in Sunday's win over the Commanders and is now in the league's concussion protocol. He'll need to clear the five steps to suit up in Week 10 against the Cardinals, and his progress should become clearer as the week progresses.

Bethune was limited in Wednesday's practice due to a thigh injury, Cam Inman of The San Jose Mercury News reports.

Bethune recorded a career-high 16 combined tackles during the 49ers' Week 9 win over the Giants while playing every single defensive snap, but he appears to have come out of that contest with a thigh injury. He had his practice snaps limited Wednesday, and he'll have two more opportunities to practice fully and avoid an injury designation heading into Sunday's NFC West clash against the Rams. Bethune has logged 40 tackles (16 solo) and one pass defense in the last three games that he's started, which coincided with Fred Warner's season-ending ankle injury that he sustained against the Buccaneers in Week 6.

Jones (knee) was estimated to be limited practice participant at Wednesday's walkthrough, John Boyle of the Seahawks' official site reports.

Jones suffered a knee injury partway through Sunday Night Football. The issue appeared potentially to be serious, but his ability to participate in practice to start the week is a positive sign for his availability in Week 10 against the Cardinals.

Wilson (ribs) was estimated to be a nonparticipant at Wednesday's walkthrough, Zach Gershman of the Cardinals' official website reports.

Wilson suffered an injury to his ribs in the team's 27-17 win over the Cowboys, and he's now opened the week on the sidelines at practice. The linebacker will have two more chances to return to practice prior to Sunday's contest in Seattle.

The Lions signed Summers (thumb) to the active roster from their practice squad Wednesday, Allen Park of Michigan Live reports.

Summers has already appeared in three games with Detroit, logging one tackle while playing exclusively on special teams. The 29-year-old also managed to return to practice Wednesday after suffering a thumb injury in the Week 9 loss to the Vikings.

Floyd (hamstring) did not practice Wednesday, Marc Raimondi of ESPN.com reports.

Floyd sustained a hamstring injury during the Falcons' Week 9 loss to the Patriots and was unable to return. He sat out of the first practice of Week 10 prep, but the veteran will have two more chances to practice in at least a limited capacity ahead of Sunday's game against the Colts in Germany. Arnold Ebiketie and rookie first-rounder James Pearce would be in line for more snaps in Week 10 if Floyd is not cleared to play.