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Michael Carter RB | TEN
Jets' Michael Carter: Seven touches in win at Lambeau
Carter rushed six times for 41 yards and caught his only target for six yards in Sunday's 27-10 win over Green Bay.
The Jets used Breece Hall (20 carries for 116 yards and a touchdown) as a workhorse in a game that started out as a defensive struggle before New York's running game got going. That left change-of-pace duties for Carter, who was effective in the limited role. Carter set a single-game season high by averaging 6.8 yards per carry in this one, bumping his season mark up to 3.8 heading into a Week 7 trip to Denver.
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Christian McCaffrey RB | SF
Panthers' Christian McCaffrey: One-man offense in loss
McCaffrey carried the ball 13 times for 69 yards and caught seven of eight targets for 89 yards in Sunday's 24-10 loss to the Rams.
The star running back got almost no help from the rest of the Panthers roster -- every other pass-catcher combined for only six receptions and 30 receiving yards while the team's other runners managed just 24 yards on the ground, and Carolina's only touchdown on the day was provided by the defense. McCaffrey will likely remain the center of both the offensive game plan and trade rumors heading into a Week 7 clash with the Buccaneers.
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Kenyan Drake RB | GB
Ravens' Kenyan Drake: Steps up in second half
Drake rushed the ball 10 times for 119 yards and a touchdown in Sunday's 24-20 loss to the Giants. He added one reception for eight yards.
Drake was involved throughout the game but served as the team's primary rusher in the second half after J.K. Dobbins was held out with knee tightness. Drake was a driving force behind the offense, as he ripped off two 30-yard rushes -- one of which went for a touchdown -- and another 21-yard gain. He entered Sunday's matchup having averaged only 3.1 yards per carry and no rushes of more than 20 yards across 21 carries, so it's unclear at best whether he may be able to replicate these results moving forward. His opportunity will also be -- at least in part -- dictated by the health of both Dobbins and Gus Edwards (knee).
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Trey Sermon RB | ATL
Eagles' Trey Sermon: Labeled inactive for SNF
Sermon (coach's decision) is inactive for Sunday's game versus the Cowboys.
Sermon won't suit up Sunday night against Dallas due to a coach's decision, after he rushed for a total of 19 yards on two carries across Philadelphia's last two contests. Following the team's bye in Week 7, the second-year running back will have a chance to play in Week 8 against Pittsburgh.
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Alvin Kamara RB | NO
Saints' Alvin Kamara: High volume in losing effort
Kamara rushed 19 times for 99 yards and caught six of nine targets for 25 yards in Sunday's 30-26 loss to the Bengals.
Kamara churned out his second consecutive strong fantasy performance playing behind fill-in starting quarterback Andy Dalton. While it is currently unclear who will be under center for New Orleans next week -- or on a given drive -- it has become crystal clear that the team's star running back is getting healthier. The 26-year-old played in back-to-back games for the first time this season, averaging 159.0 yards from scrimmage over that span. It is fortunate timing for fantasy managers that Kamara looks healthy, as the Saints have a quick turnaround in a Thursday matchup with Arizona to kick off Week 7.
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James Robinson RB | NO
Jaguars' James Robinson: Team-high carry total in loss
Robinson rushed 12 times for 54 yards and secured his only target for one yard in the Jaguars' 34-27 loss to the Colts on Sunday.
Robinson's carry total was a team-high figure, although backfield mate Travis Etienne was only two rush attempts behind him and outgained him by 32 yards. Robinson was at least more efficient Sunday against a tough defense after gaining just 56 yards on 18 carries over his last two games, and he'll aim to continue climbing in a Week 7 home battle versus the Giants.
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Travis Etienne RB | NO
Jaguars' Travis Etienne: Team-high rushing total in loss
Etienne rushed 10 times for 86 yards and secured both targets for 22 yards in the Jaguars' 34-27 loss to the Colts on Sunday. He also committed a fumble recovered by Jacksonville.
Etienne's rushing yardage total was both a team- and career-high figure, and he's now encouragingly logged double-digit carries in three of his last four games. Etienne naturally continues to be consistently involved in the passing game as well, although his target total Sunday was his second lowest yet. The second-year pro will aim to continue on a positive trajectory in a Week 7 home matchup against the Giants.
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Raheem Mostert RB | LV
Dolphins' Raheem Mostert: Modest production in loss
Mostert rushed 14 times for 49 yards and secured one of two targets for minus-1 yard in the Dolphins' 24-16 loss to the Vikings on Sunday.
The veteran back shook off the knee issue he'd dealt with during the week as expected, but Mostert ultimately found the going against the Vikings run defense tough more often than not. Game script eventually turned against Mostert once the Dolphins fell behind 16-3 early in the fourth quarter. However, Mostert continued to function as the clear lead back for Miami, an encouraging trend that's expected to continue in a Week 7 home Sunday night matchup against the Steelers.
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Joe Mixon RB | HOU
Bengals' Joe Mixon: Nabs receiving TD in win
Mixon rushed eight times for 45 yards and caught four of five targets for 23 yards and a touchdown in Sunday's 30-26 win over the Saints.
Joe Burrow (300 yards and four scores) and Ja'Marr Chase (132 yards and two scores) stole the show at the Superdome, but Mixon was able to get in on the fantasy goodness with his first receiving touchdown of the season. The veteran did see his carries decline for the third game in a row, but he also received 80 percent of the backfield touches, maintaining his status as Cincinnati's lead back over Samaje Perine (two carries for five yards). Mixon has also been more efficient over his last two contests (5.6 YPC) compared to earlier in the year, which is a positive signal heading into a favorable matchup against Atlanta next Sunday.
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Dalvin Cook RB | DAL
Vikings' Dalvin Cook: Salvages day with long TD
Cook rushed 13 times for 77 yards and a touchdown and brought in his only target for six yards in the Vikings' 24-16 win over the Dolphins on Sunday.
Cook was having a positively pedestrian day against an active Dolphins run defense until he shook loose for a 53-yard touchdown run two plays after the defense recovered a Jaylen Waddle fumble late in the fourth quarter. The score, Cook's fourth of the year overall, turned out to be the difference in the game after Miami scored a late touchdown, and the yardage tally was Cook's fourth straight of greater than 70 yards. He'll aim to finally eclipse the century mark when the Vikings return to action for an Oct. 30, Week 8 home matchup versus the Cardinals following a Week 7 bye.