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Tony Pollard RB | TEN
Cowboys' Tony Pollard: Modest output on 13 touches
Pollard rushed 11 times for 44 yards and caught two of three targets for eight yards in Sunday's 26-17 loss to the Eagles.
Pollard tied his season high in touches with 13, but he was bottled up outside of an isolated 15-yard rush. Veteran counterpart Ezekiel Elliott looked like the more explosive back in a tough matchup against Philly's defense, which doesn't line up with the trends we saw from both players through Dallas' previous five contests. The good news for Pollard's fantasy managers is that the Lions and their 32nd-ranked rush defense are on tap next Sunday.
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Ezekiel Elliott RB | LAC
Cowboys' Ezekiel Elliott: Runs hard on SNF
Elliott rushed 13 times for 81 yards and a touchdown while catching his lone target for five yards in Sunday's 26-17 loss to Philadelphia.
Elliott put together a vintage performance and led the Cowboys in all rushing categories despite the losing effort. The veteran was beginning to show some wear after a couple of high-volume, low-efficiency games in a row, so his game-high mark of 6.2 yards per rush was a welcome sight. Fellow tailback Tony Pollard finished with two less carries and was uncharacteristically less efficient than Zeke. Both of Dallas' backs could put up big numbers next Sunday against the Lions, who enter Week 7 with the worst rush defense in the league.
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Matt Breida RB | SF
Giants' Matt Breida: Nets 11 yards in win
Breida rushed three times for minus-six yards and caught both of his targets for 17 yards in Sunday's 24-20 win over Baltimore.
Breida couldn't get going on the ground, as his first two carries went for negative yardage and his third produced only one yard. However, he did make an impact on a second-quarter drive that ended with the team's first touchdown, gaining 17 yards on a pair of receptions. Breida remains firmly entrenched behind workhorse running back Saquon Barkley on the depth chart, so he won't have much fantasy value unless Barkley is forced to miss time.
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Miles Sanders RB | DAL
Eagles' Miles Sanders: Leads rushing attack with TD
Sanders rushed 18 times for 71 yards and a touchdown while catching his lone target for one yard in Sunday's 26-17 win over Dallas.
Sanders bounced back from a down game last week with an encouraging effort on national television. The 25-year-old finished with 12 more carries than the next Philadelphia running back (Kenneth Gainwell), confirming his prime fantasy status as the lead back on a dynamic offense. Fantasy managers will have to find a replacement for the RB1 heading into the Eagles' upcoming bye week. Sanders and his 105/485/4 rushing line will return rejuvenated for a Week 8 matchup against the Steelers on Oct. 30.
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Eno Benjamin RB | NO
Cardinals' Eno Benjamin: Produces as pass catcher
Benjamin rushed the ball 15 times for 37 yards in Sunday's 19-9 loss to the Seahawks. He added three receptions for 28 yards.
Benjamin accounted for 15 of the team's 18 carries by running backs, though Kyler Murray also tallied 10 rushing attempts. Benjamin was bottled up on the ground and his longest gain went for only six yards. He salvaged his day with his work as a receiver and managed to rack up 65 total yards. It remains to be seen whether James Conner (ribs) or Darrel Williams (knee) will be able to return in Week 7, but the Cardinals play Thursday, which could lead to Benjamin getting another turn as the team's lead back.
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Kenneth Walker III RB | KC
Seahawks' Kenneth Walker: Dominates work, looks good
Walker carried the ball 21 times for 97 yards and a touchdown in Sunday's 19-9 win over Arizona. He added two receptions for 13 yards.
Walker dominated carries out of Seattle's backfield as expected in the first week without Rashaad Penny (ankle), accounting for 21 of the team's 30 rushing attempts. He displayed some big-play ability by ripping off gains of 34, 21 and 17 yards, and he also recorded an 11-yard rushing score. While Walker isn't known for his receiving ability, it was encouraging to see him involved in the passing game -- even at a minimal level. Walker should carry a heavy workload once again in Week 7 against the Chargers.
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Jeff Wilson RB | MIA
49ers' Jeff Wilson: Putrid results in defeat
Wilson rushed seven times for 25 yards while losing a fumble and failing to haul in his lone target in Sunday's 28-14 loss to the Falcons.
Wilson got off to a rough start, coughing up the ball on a short rushing attempt that led to a defensive touchdown and an early 14-0 lead for Atlanta. The 26-year-old entered Sunday's tilt coming off of his best performance of the season (17/120/1), which makes Sunday's dud in a soft matchup even more debilitating for those relying on the hot early season waiver add. San Francisco is suffering from a severe lack of depth at the running back position, so Wilson remains the starter and workhorse -- barring a trade for Christian McCaffrey -- heading into a matchup against Kansas City next Sunday.
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Clyde Edwards-Helaire RB | KC
Chiefs' Clyde Edwards-Helaire: Held in check by Buffalo
Edwards-Helaire carried the ball nine times for 33 yards in Sunday's 24-20 loss to the Bills.
The Kansas City running game got stifled by the Buffalo front seven, but Edwards-Helaire also wasn't able to add any value through the air as he failed to even see a target for the first time this season. The running back does have five TDs through six games, but he could struggle to get into the end zone or gain much yardage in Week 7 against the 49ers' tough run defense.
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D'Ernest Johnson RB | TEN
Browns' D'Ernest Johnson: Gathers two catches in loss
Johnson caught two of two targets for nine yards in Sunday's 38-15 loss to the Patriots in Week 6.
Johnson had his most significant contributions of the season yet, but he remains a fringe player on offense. As long as Nick Chubb and Kareem Hunt are healthy, Johnson will play a limited role.
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Devin Singletary RB | NYG
Bills' Devin Singletary: Triple-digit scrimmage yards
Singletary carried the ball 17 times for 85 yards and caught four of five targets for 22 yards in Sunday's 24-20 win over Kansas City.
For the first time this season, Singletary reached the century mark in scrimmage yards, although he'd topped 90 yards in two of the prior three games. While his production is trending up, the running back has still scored only one touchdown through six games in an offense dominated by Josh Allen heading into the Bills' Week 7 bye.