Vaki (hamstring) is active for Sunday's game against the Vikings.

A hamstring injury limited Vaki's practice participation all week, but he has been cleared to play in Sunday's NFC North tilt. He'll serve as the Lions' RB3 behind Jahmyr Gibbs and David Montgomery due to Craig Reynolds (hamstring) being inactive.

Pierce (coach's decision) is inactive for Sunday's game against the Broncos.

The running back is now a healthy scratch for the fifth time in eight games this season. Nick Chubb and Woody Marks continue to hold down Houston's backfield. Pierce has played on just 23 offensive snaps this year, carrying the ball 10 times for 26 yards and no scores.

Carter (coach's decision) is inactive for Sunday's game against the Patriots, Marc Raimondi of ESPN.com reports.

Carter played two snaps on offense during the Falcons' Week 8 loss against the Dolphins and turned two carries into 14 yards. However, the undrafted rookie will be a healthy scratch for Sunday's contest in New England, as the Falcons go with Bijan Robinson and Tyler Allgeier as their two active running backs.

Pacheco (knee), who is out for Sunday's game against the Bills, should be back after the Chiefs' Week 10 bye, Tracy Wolfson of CBS Sports reports.

Per Wolfson, coach Andy Reid indicated that Pacheco avoided a serious injury, which gives the running back a chance to return to action Nov. 16 against the Broncos. In his absence Sunday, Kareem Hunt, Brashard Smith and Clyde Edwards-Helaire are expected to carry Kansas City's backfield load, with Elijah Mitchell a candidate to be active versus Buffalo as well.

Kamara (ankle), who is questionable for Sunday's Week 9 matchup against the Rams, is expected to play, Ian Rapoport of NFL Network reports.

Kamara again dealt with an ankle injury throughout the week and logged a trio of limited practices. Saints coach Kellen Moore said Friday that the star running back was trending in the right direction, and it now appears likely that Kamara will suit up. However, he logged a season-low 51 percent snap share last Sunday while managing the same nagging ankle issue, so it remains to be seen if he'll have a full workload even if he does play.

Johnson (hamstring) has been ruled out ahead of Sunday's game against the Broncos.

Johnson landed on injured reserve with a hamstring injury after Week 3 and returned to practice Wednesday. He turned in full practice sessions Thursday and Friday but will wait until at least Week 10 to be activated.

Patterson was elevated from the Chargers' practice squad to the active roster Saturday.

Patterson will be elevated to the active roster for the second straight week as the Chargers have an injury-riddled running back room. He had 11 rushing attempts in a blowout win over the Vikings in Week 8 and could be the primary change-of-pace back to Kimani Vidal in Week 9.

Johnson was elevated from the Chargers' practice squad to the active roster Saturday.

Johnson has spent the entire regular season with the Chargers' practice squad, and Sunday will mark his first chance to be active on game day. He could have a small offensive role, as Kimani Vidal will be the only healthy running back that is currently signed to the active roster for a Week 9 matchup against the Titans.

Johnson was elevated from the Patriots' practice squad to the active roster Saturday.

With Rhamondre Stevenson (toe) ruled out for Sunday's contest with the Falcons, Johnson gets the elevation. He will likely share backup work with Terrell Jennings behind TreVeyon Henderson, who is slated to be the Patriots' lead back.

Nichols was elevated from the Steelers' practice squad to the active roster Saturday.

Nichols has been on the Steelers' practice squad all season. If he is active for game day and enters Sunday's game against the Colts, it will mark his first regular-season snaps as a pro. Per Brian Batko of the Pittsburgh Post-Gazette, Nichols will line up for a special teams role, if active.