Pierce is inactive for Monday night's game against the Buccaneers.
With Pierce a healthy scratch, Dare Ogunbowale, Woody Marks and British Brooks are available to work behind Nick Chubb in the Texans' Week 2 backfield. In Houston's season-opening 14-9 loss to the Rams, Pierce logged just seven snaps on offense en route to carrying three times for five yards and not hauling in his only target.