McCaffrey is a candidate to be rested in Friday's preseason game against the Bills, David Newton of ESPN.com reports.
Newton notes that for the time being, the Panthers appear to be trending toward playing a number of their starters in the contest, but McCaffrey could be held out of the contest. Given the extensive time McCaffrey has missed due to injuries the past two seasons, Carolina has extra incentive to keep him healthy in advance of Week 1.