Mays (wrist) was placed on injured reserve by the Lions on Sunday with a designation to return, Tom Pelissero of Netflix reports.
Mays suffered a fractured wrist during the preseason, and he will now be forced to miss at least four games to open the regular season. The 27-year-old was expected to operate as the team's starting center this year, so in his absence, Seth McLaughlin will get a chance to handle that role to open 2026.