McCaffrey (calf/Achilles) is listed as questionable for Monday's game against the Jets, Nick Wagoner of ESPN.com reports.
McCaffrey said Friday that he will be available for the season opener, and while the expectation remains that he'll be cleared ahead of Monday's 8:15 p.m. ET kickoff, his questionable designation could hint that the 49ers plan to manage his workload. Regardless of McCaffrey's availability and touch count in Week 1, Jordan Mason should be primed for some work as the primary backup to the star running back.