Pannone (0-1) took the loss Wednesday against the Giants, allowing three runs (two earned) on three hits and two walks over three innings. He struck out two.
Making his first appearance in the majors since 2023, Pannone got through the first inning unscathed before giving up a three-run homer to Daniel Susac in the second. Following Wednesday's spot start, the left-handed Pannone figures to head back to Triple-A Nashville, where he's posted a 3.96 ERA across 75 innings this season.