The Brewers designated Pannone for assignment Friday, Hunter Baumgardt of Fox Sports 920 Milwaukee reports.
Pannone was called up to make a spot start for the Brewers on Wednesday, during which he gave up three runs (two earned) across three innings. Now that his services are no longer required by the big club, he'll lose his place on the active and 40-man rosters to make room for DL Hall (pectoral), who returned from the injured list Friday.