Jaguars vs. 49ers Live updates Score, results, highlights, for Sunday's NFL game

The San Francisco 49ers have enjoyed the comforts of home their last two games, but now they must head out on the road. They will take on the Jacksonville Jaguars at 1 p.m. ET on Sunday at TIAA Bank Field. The 49ers should still be riding high after a big victory, while Jacksonville will be looking to regain their footing.

San Francisco took their contest against the Los Angeles Rams this past Monday by a conclusive 31-10 score. San Francisco's WR Deebo Samuel did his thing and punched in one rushing touchdown in addition to catching five passes for one TD and 97 yards.

Meanwhile, Jacksonville was within a late touchdown of stealing the win, but they took the "L" against the Indianapolis Colts 23-17. WR Jamal Agnew put forth a good effort for the losing side as he punched in one rushing touchdown. That touchdown -- a 66-yard rush in the first quarter -- was one of the highlights of the game.

San Francisco is the favorite in this one, with an expected 6.5-point margin of victory. Those who got lucky with them against the spread this past Monday might want to hold off on placing bets this time since the squad has yet to string together back-to-back wins against the spread.

The 49ers' victory brought them up to 4-5 while the Jaguars' loss pulled them down to 2-7. San Francisco is 1-2 after wins this year, and Jacksonville is 2-4 after losses.

Updates
(72)
See New Posts
 
Pinned
Link copied
@Jaguars via Twitter
November 21, 2021, 9:40 PM
Nov. 21, 2021, 4:40 pm EST
 
Pinned
Link copied
@49ers via Twitter
November 21, 2021, 9:32 PM
Nov. 21, 2021, 4:32 pm EST
 
Pinned
Link copied
@Jaguars via Twitter
November 21, 2021, 9:30 PM
Nov. 21, 2021, 4:30 pm EST
 
Pinned
Link copied
@49ers via Twitter
November 21, 2021, 9:21 PM
Nov. 21, 2021, 4:21 pm EST
 
Pinned
Link copied
@Jaguars via Twitter
November 21, 2021, 9:20 PM
Nov. 21, 2021, 4:20 pm EST
 
Pinned
Link copied
@49ers via Twitter
November 21, 2021, 9:13 PM
Nov. 21, 2021, 4:13 pm EST
 
Pinned
Link copied
@Jaguars via Twitter
November 21, 2021, 9:11 PM
Nov. 21, 2021, 4:11 pm EST
 
Pinned
Link copied
@49ers via Twitter
November 21, 2021, 9:11 PM
Nov. 21, 2021, 4:11 pm EST
 
Pinned
Link copied
@49ers via Twitter
November 21, 2021, 9:10 PM
Nov. 21, 2021, 4:10 pm EST
 
Pinned
Link copied
@49ers via Twitter
November 21, 2021, 9:03 PM
Nov. 21, 2021, 4:03 pm EST
 
Pinned
Link copied
@49ers via Twitter
November 21, 2021, 9:01 PM
Nov. 21, 2021, 4:01 pm EST
 
Pinned
Link copied
@49ers via Twitter
November 21, 2021, 8:58 PM
Nov. 21, 2021, 3:58 pm EST
 
Pinned
Link copied
@Jaguars via Twitter
November 21, 2021, 8:54 PM
Nov. 21, 2021, 3:54 pm EST
 
Pinned
Link copied
@Jaguars via Twitter
November 21, 2021, 8:48 PM
Nov. 21, 2021, 3:48 pm EST
 
Pinned
Link copied
@49ers via Twitter
November 21, 2021, 8:48 PM
Nov. 21, 2021, 3:48 pm EST
 
Pinned
Link copied
@Jaguars via Twitter
November 21, 2021, 8:39 PM
Nov. 21, 2021, 3:39 pm EST
 
Pinned
Link copied
@49ers via Twitter
November 21, 2021, 8:33 PM
Nov. 21, 2021, 3:33 pm EST
 
Pinned
Link copied
@Jaguars via Twitter
November 21, 2021, 8:24 PM
Nov. 21, 2021, 3:24 pm EST
 
Pinned
Link copied
@49ers via Twitter
November 21, 2021, 8:22 PM
Nov. 21, 2021, 3:22 pm EST
 
Pinned
Link copied
@49ers via Twitter
November 21, 2021, 8:19 PM
Nov. 21, 2021, 3:19 pm EST
 
Pinned
Link copied
@Jaguars via Twitter
November 21, 2021, 8:11 PM
Nov. 21, 2021, 3:11 pm EST
 
Pinned
Link copied
@49ers via Twitter
November 21, 2021, 8:11 PM
Nov. 21, 2021, 3:11 pm EST
 
Pinned
Link copied
@49ers via Twitter
November 21, 2021, 7:50 PM
Nov. 21, 2021, 2:50 pm EST
 
Pinned
Link copied
@49ers via Twitter
November 21, 2021, 7:49 PM
Nov. 21, 2021, 2:49 pm EST
 
Pinned
Link copied
@Jaguars via Twitter
November 21, 2021, 7:36 PM
Nov. 21, 2021, 2:36 pm EST
 
Pinned
Link copied
@49ers via Twitter
November 21, 2021, 7:26 PM
Nov. 21, 2021, 2:26 pm EST
 
Pinned
Link copied
@49ers via Twitter
November 21, 2021, 7:22 PM
Nov. 21, 2021, 2:22 pm EST
 
Pinned
Link copied
@49ers via Twitter
November 21, 2021, 7:21 PM
Nov. 21, 2021, 2:21 pm EST
 
Pinned
Link copied
@Jaguars via Twitter
November 21, 2021, 7:21 PM
Nov. 21, 2021, 2:21 pm EST
 
Pinned
Link copied
@Jaguars via Twitter
November 21, 2021, 7:10 PM
Nov. 21, 2021, 2:10 pm EST
See More
Now Playing
Share Video
Link copied!
  • Image thumbnail
    1:31

    Drew Bledsoe sees similarities to Josh Allen in this QB prospect

  • Image thumbnail
    1:55

    NFL Draft Quarterback Comparison: Carson Beck

  • Image thumbnail
    1:46

    Assessing Ty Simpson As a 1st Round Draft Pick

  • Image thumbnail
    1:41

    Pick Your QB: Shedeur Sanders Or Ty Simpson

  • Image thumbnail
    1:54

    Pick Your QB: Will Howard Or Ty Simpson

  • Image thumbnail
    1:41

    Pick Your Duo: Mendoza/Jeanty Or Ward/Love

  • Image thumbnail
    1:39

    Who They Should Take NFL Mock Draft: Where Does Jeremiyah Love End Up?

  • Image thumbnail
    1:34

    Who They Should Take NFL Mock Draft: Who Do The Giants Select?

  • Image thumbnail
    1:11

    Who They Should Take NFL Mock Draft: Mansoor Delane To Tampa Bay

  • Image thumbnail
    1:46

    Who They Should Take NFL Mock Draft: Kansas City At No. 9

  • Image thumbnail
    1:32

    Who They Should Take NFL Mock Draft: Which Receiver For The Rams?

  • Image thumbnail
    0:48

    5 Teams Who Are Still In Deep Decision Mode: Cleveland Browns

  • Image thumbnail
    0:56

    5 Teams Who Are Still In Deep Decision Mode: Miami Dolphins

  • Image thumbnail
    0:45

    5 Teams Who Are Still In Deep Decision Mode: Dallas Cowboys

  • Image thumbnail
    1:03

    5 Teams Who Are Still In Deep Decision Mode: Carolina Panthers

  • Image thumbnail
    0:59

    5 Teams Who Are Still In Deep Decision Mode: Chicago Bears

  • Image thumbnail
    1:14

    Is Signing Odell Beckham A Smart Move For The Giants?

  • Image thumbnail
    1:03

    Zac Taylor Sounds Off After Dexter Lawrence Addition

  • Image thumbnail
    0:59

    Steelers Have Had " Great Communication" With Rodgers

  • Image thumbnail
    1:38

    Odds Shift Back In Favor Of Arvell Reese At No. 2 For The Jets

This page may contain affiliate links. If you click and sign up, make a deposit, or place a wager, we may earn a commission at no additional cost to you.