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Inside the Lines team

Cleveland is riding a five-game winning streak entering the third game of its four-game series against Kansas City on Wednesday night. Star third baseman Jose Ramirez homered against the Royals on Tuesday, which was his 28th homer of the season. He also went yard against Tampa Bay last Thursday, as he continues to close in on back-to-back 30-homer campaigns. Ramirez is +475 to homer against the Royals during the Wednesday MLB schedule. 

The Guardians vs. Royals game begins at 6:40 p.m. ET, and Ramirez is one of the top MLB HR bets from SportsLine's Inside the Lines team. MLB home run props are available for almost every player in every game at various sportsbooks, and SportsLine's proven computer model can help you find value for your MLB betting picks. New users can also use the latest bet365 bonus code to receive $300 in bonus bets instantly after your first $5 wager, and take advantage of one of the best sportsbook promos:

The SportsLine Projection Model simulates every MLB game 10,000 times. It's up 54.25 units on its individual MLB HR picks this season after nailing Kyle Manzardo (+420) to homer last Thursday and Colson Montgomery (+575) last Friday. It has called two three-leg parlays paying at least 80-1 this season. Now, the model and SportsLine's team of Data Scientists have revealed their betting projections for some of the most-bet MLB HR prop bets on Wednesday. You can find even more picks in their daily blog.

Best MLB home run picks for Wednesday, September 10:

MLB Best Home Run Bets 9/10

For more real-time, free picks every day: Inside the Lines Blog.

Willy Adames, Giants (+500, Caesars)

This is an interesting spot for Adames, who is 0-11 with 5 strikeouts in his career against Eduardo Rodriguez. However, if there's a time for Adames to break through, it's now—Rodriguez is having the worst season of his career with a 1.600 WHIP. He's allowed 17 of his 21 HRs to right-handed batters. Adames homered yesterday and now has 10 HRs in his last 24 games. Despite hitting just .201 against lefties, he has a higher slugging percentage against them, with 10 of his 28 hits going for HRs. We set Adames' line at +330 to homer. Claim the latest Caesars promo code here, where new users get twenty 100% sportsbook profit boosts with a $1 bet when they use code CBS20X:

Jose Ramirez, Guardians (+475, BetMGM)

Ramirez homered yesterday as part of a three-hit performance and is now batting close to .300 with a .925 OPS in home games. He also has a .913 OPS and 23 of his 28 HRs in games when facing a right-handed pitcher. Ramirez is 1-1 with a double in his career against Jonathan Bowlan. Bowlan has allowed 4 HRs in just 4.2 IP as a starter, though he's been more effective as a reliever. We set Ramirez's line at +340 to homer, and you can get this price as well as up to $1,500 in bonus bets back if your first wager loses when using the latest BetMGM bonus code:

Colson Montgomery, White Sox (+450, FanDuel)

Since hitting his first HR on July 22, Montgomery has only gone three or more games without a homer twice—and he's currently on a three-game drought, so he's due. Of his 45 career hits, 18 have been home runs, and 10 of his 20 hits at home have left the yard. The Rays are going with a bullpen game, so exact matchups are unclear, but we expect him to see a couple of RHPs. We set Montgomery's line at +390 to homer. Bet this prop with the latest FanDuel promo code and get $300 in bonus bets if your first wager of $5+ wins:

Where to bet MLB props on Wednesday

Here is a look at betting sites that will offer MLB HR props on Wednesday: 

SportsbookBonus offer Promo code

Caesars

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BetMGM 

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FanDuel 

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DraftKings 

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bet365 

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More MLB picks for Wednesday 

You've seen the model's MLB HR prop picks for several players on Wednesday. Now, get MLB projections for every player prop at SportsLine.

Need more from SportsLine? See today's best MLB picks from SportsLine's Angelo Magliocca, who is on a 69-47 roll (+1565) on MLB picks.