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Inside the Lines team

Before signing with the Cubs in 2022 as an international signing, Seiya Suzuki was known for his power in Japan, slugging 25 home runs or more in a season on six occasions. However, that power didn't exactly translate immediately to the United States, as Suzuki topped out at 21 homers during his first three years in Chicago. However, he's found another gear in 2025 and enters a Wednesday matchup with the Giants sitting on 27 home runs for the season. Suzuki hasn't homered in the last 18 games, but that's helped swell his price to +450 in the latest MLB home runs odds.

The wind will be blowing out to left-center in San Francisco on Wednesday night and Suzuki gets a lefty vs. righty matchup with Carson Whisenhunt on the mound, which is why he's one of our top MLB HR picks. MLB home run props are available for almost every player in every game at various sportsbooks, and SportsLine's proven computer model can help you find value for your MLB betting picks. New users can also use the latest bet365 bonus code to receive $200 in bonus bets instantly after your first $5 wager, and take advantage of one of the best sportsbook promos:

The SportsLine Projection Model simulates every MLB game 10,000 times. It's up 56.75 units on its individual MLB HR picks this season after nailing Matt Wallner (+425) and Zachary Neto (+460) to homer on Tuesday, and has called two three-leg parlays paying at least 80-1 this season. Now, the model and SportsLine's team of Data Scientists have revealed their betting projections for some of the most-bet MLB HR prop bets on Wednesday. You can find even more picks in their daily blog.

Best MLB home run picks for Wednesday, August 27:

MLB Best Home Run Bets 8/27

For more real-time, free picks every day: Inside the Lines Blog.

Seiya Suzuki, Cubs (+450, DraftKings)

Suzuki has just 2 HRs over his last 35 games in the second half of the season, but a matchup against a rookie LHP might be what he needs to get back on track. He has an .877 OPS against left-handed pitchers this season. Right-handed hitters have a 1.074 OPS against Giants' SP Carson Whisenhunt in his first four career starts. We set Suzuki's line at +390 to homer and you can bet this MLB player prop at DraftKings, where you can get $300 in bonus bets instantly and over $200 off on NFL Sunday Ticket with the latest DraftKings promo code:

Hunter Goodman, Rockies (+600, FanDuel)

Goodman is facing Framber Valdez, who doesn't give up many HRs, but this +600 price is a solid value play according to our model. Valdez hasn't been at his best lately, allowing 3 or more earned runs in each of his last 4 starts. While he's only given up 9 HRs this season, 8 of those have come against right-handed bats. Goodman has a strong .856 OPS against left-handed pitchers and has actually shown more power on the road, with 16 of his 26 HRs coming away from Coors Field. We set Goodman's line at +420 to homer. You can get over $300 in bonus bets if your first wager of $5 or more wins when you bet $5 using the latest FanDuel promo code:

Christian Yelich, Brewers (+560, FanDuel)

Yelich enters today with 4 straight multi-hit games. He hasn't homered during that stretch, but he's swinging a hot bat. Yelich has hit 22 of his 26 HRs this season against RHPs. While Rhyne Nelson doesn't give up many HRs overall, 10 of his 13 allowed have come on the road. We set Yelich's line at +360 to homer, so you're getting an extra 200 points of juice from FanDuel here.

Where to bet MLB props on Wednesday

Here is a look at betting sites that will offer MLB HR props on Wednesday: 

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Caesars

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FanDuel 

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DraftKings 

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bet365 

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More MLB picks for Wednesday 

You've seen the model's MLB HR prop picks for several players on Wednesday. Now, get MLB projections for every player prop at SportsLine.

Need more from SportsLine? See today's best MLB picks from SportsLine's Angelo Magliocca, who is on a 58-40 roll (+1422) on MLB picks.