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David Montgomery RB | HOU
Lions' David Montgomery: May face multi-week recovery
Montgomery (thigh) said it will take him "a couple weeks" to get fully healthy after being forced out of Sunday's 37-31 overtime loss to the Seahawks late in the third quarter, Adam Schefter of ESPN reports.
Coach Dan Campbell said Montgomery suffered a bruised thigh. It remains to be seen whether the veteran running back will be able to play through the injury before returning to full strength, or whether he could be facing a multi-game absence. In either scenario, the Lions figure to lean more heavily on rookie first-round pick Jahmyr Gibbs, beginning in Week 3 versus the Falcons. Craig Reynolds could also potentially handle an expanded depth role.
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Cam Akers RB | SEA
Rams' Cam Akers: Team engaged in trade talks
The Rams have engaged in trade talks involving Akers, who was a healthy scratch for Sunday's 30-23 loss to the 49ers, Ian Rapoport of NFL Network reports.
Akers' spot on Los Angeles' roster once again seems up in the air, a familiar situation after he demanded a trade early in the 2022 season -- although unlike last year, Rapoport reports that no significant issues have arisen between the running back and the team this time around. Akers closed out the 2022 campaign with three straight 100-yard rushing performances, so it's possible he could draw interest from a team in need of backfield help. Meanwhile, Kyren Williams scored twice operating as the Rams' starting running back versus San Francisco while compiling 100 scrimmage yards, and he seems firmly in the top role regardless of what happens with Akers.
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Samaje Perine RB | CIN
Broncos' Samaje Perine: Quiet in loss
Perine carried once for four yards and secured three of his four targets for 20 yards in Sunday's 35-33 loss to the Commanders.
Despite leading all Denver running backs in offensive snaps, Perine was unable to get much going for fantasy purposes. The veteran's 50 percent snap share was just over that of teammate Javonte Williams, who reached a 45 percent snap share in the contest. With that said, Williams was much more involved in the game plan with 12 carries and three targets. It's possible that Perine could continue to see a dip in touches as Williams proves he can handle a normal workload. Nonetheless, the 28-year-old Perine will look to have a bounce-back performance when the Broncos visit the Dolphins in Week 3.
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Latavius Murray RB | BUF
Bills' Latavius Murray: Works ahead of Harris
Murray carried the ball six times for 22 yards and one touchdown in Sunday's 38-10 win over the Raiders. He added two receptions on two targets for nine yards.
James Cook served as the lead back for the Bills, but Murray mixed in as early as the second possession. He capped that drive with a four-yard touchdown plunge and was also regularly on the field when the ball was inside the opponent's 10-yard line. That role will leave him as a touchdown-or-bust option, but it appears that he has jumped Damien Harris on the depth chart.
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De'Von Achane RB | MIA
Dolphins' De'Von Achane: Quiet pro debut
Achane (shoulder) had one carry for five yards and caught his lone target for four yards in Sunday's 24-17 win over the Patriots.
Achane was able to make his NFL debut after missing the Dolphins' first game due to a shoulder injury sustained in the preseason. The third-round rookie was used sparingly as starter Raheem Mostert carried the offense with 121 rushing yards and two scores. Fellow backup Salvon Ahmed suffered a groin injury in Sunday's win, so Achane may see his role increase against the Broncos next Sunday.
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Antonio Gibson RB | NE
Commanders' Antonio Gibson: Stuck in small role
Gibson had two carries for nine yards while catching all three of his targets for 44 yards in Sunday's 35-33 win over Denver.
Gibson was limited to just five touches a week after receiving four, giving way to starter Brian Robinson, who had a two-touchdown day. The veteran backup was able to break off a 36-yard reception out of the backfield but was otherwise a non-factor. Gibson has provided fantasy value in the past while serving as Washington's starter, but he is an unappealing option against Buffalo next Sunday in his current role.
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Matt Breida RB | SF
Giants' Matt Breida: Quiet Sunday but could start Week 3
Breida rushed once for five yards and wasn't targeted in the passing game Sunday in a win against Arizona in Week 2. However, top running back Saquon Barkley injured his ankle late in the contest, making Breida a candidate to start for New York this Thursday in San Francisco.
Breida's lone rush attempt Sunday came on the play after Barkley was injured with just over a minute left in the fourth quarter. Breida logged only three touches in a season-opening loss to Dallas, emphasizing the minimal role he has on offense when Barkley is healthy. However, with the Giants' star RB slated for an MRI on his ankle Monday, per Adam Schefter of ESPN, the door appears to be open for Breida to move in as the team's starter Thursday in San Francisco and possibly for additional time beyond that. The matchup against the 49ers is far from ideal, and there is hope among the organization that Barkley avoided a high-ankle sprain, so fantasy managers have a lot to consider when weighing how much to invest in grabbing Breida off the waiver wire.
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Raheem Mostert RB | LV
Dolphins' Raheem Mostert: Carries offense with two TDs
Mostert (knee) carried the ball 18 times for 121 yards and two touchdowns while catching his lone target for six yards in Sunday's 24-17 win over the Patriots.
Mostert was already on his way to a strong performance before ripping off a 41-yard touchdown run in the fourth quarter to put the Dolphins up for good. The veteran back was not limited by the minor knee injury he was dealing with during the practice week, commanding 18 carries with no other Miami back seeing more than three. Mostert has certainly outperformed his ADP so far, and he will look to keep things rolling against the Broncos next Sunday.
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Rhamondre Stevenson RB | NE
Patriots' Rhamondre Stevenson: Finds end zone in loss
Stevenson rushed 15 times for 50 yards and a touchdown while catching all three of his targets for 10 yards in Sunday's 24-17 loss to Miami.
Stevenson was heading for another down game before a late touchdown saved his fantasy day. The 25-year-old finished ahead of veteran Ezekiel Elliott (5-13-0) in carries for the second consecutive week, confirming his status as the lead back in New England. Stevenson has just 75 rushing yards through two games, but his ground production should increase when the Patriots' brutal early season schedule softens up. There is nothing soft about the Jets' defense, which will host Stevenson and the Patriots next Sunday.
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Damien Harris RB | BUF
Bills' Damien Harris: Gets garbage-time score
Harris carried the ball seven times for 33 yards and a touchdown in Sunday's 38-10 win over the Raiders.
On the surface, it appears that Harris saw a significant uptick in involvement in the Bills offense after a one-carry performance in Week 1. However, through three quarters, he had only two carries while Latavius Murray had already tallied all eight of his touches for the day. Given that, it appears that Harris has slipped to third on the depth chart, and he could be in danger of rarely taking the field in more competitive games.