Hopkins didn't practice Wednesday due to an ankle injury, Jim Wyatt of the Titans' official site reports.
Meanwhile, fellow wideout Treylon Burks was excused from practice Wednesday for personal reasons but is expected back Thursday. With a missed session under his belt, Hopkins' status is now worth monitoring as Sunday's game against the Chargers approaches. In the Titans' Week 1 loss to the Saints, Hopkins caught seven passes (on 13 targets) for 65 yards.