Harris (hamstring) has been downgraded to out for Saturday night's game against the Colts.
With Harris unavailable, look for Rhamondre Stevenson to log plenty of carries versus Indianapolis, while Brandon Bolden (knee) is a candidate to see his share of change-of-pace touches, assuming he's active. Harris will target a possible return for the Patriots' Week 16 game against the Bills on Dec. 26.