Niese (leg) was spotted leaving the Lions' locker room in crutches after sustaining an injury in Saturday's preseason game against the Commanders, Eric Woodyard of ESPN.com reports.
Niese had his right leg crushed by a defender in Saturday's contest and is feared to have suffered an MCL sprain in his right knee. The reserve center has been a versatile piece of the Lions' offensive line and will likely need to miss time with the injury.