Jefferson is expected to serve as the top backup to D'Andre Swift in Sunday's game against the Eagles with No. 2 running back Jamaal Williams (thigh) inactive for the contest, Justin Rogers of The Detroit News reports.
Beyond Swift and Williams, none of the Lions' other running backs have played an offensive snap this season, as Jefferson (nine) and Godwin Igwebuike (116) have seen all their reps on special teams to date. Jefferson shouldn't be expected to handle Williams' typical snap share -- which has ranged between 29 and 39 percent in all but one of the Lions' seven games -- but the seventh-round rookie out of Oregon State looks like he'll at least be the next man up when Swift requires a breather.