Slayton left Sunday's game versus the Eagles due to a shoulder injury, Dan Salomone of the Giants' official site reports.
After landing on his left arm at the end of a 22-yard catch on the first drive of the contest, Slayton went to the sideline and soon after to the locker room. He was deemed questionable to return, but in the meantime, Sterling Shepard, Golden Tate and Evan Engram will be the Giants' primary pass catchers.