Chiefs head coach Andy Reid said James won't practice Wednesday due to an MCL injury, Sam McDowell of The Kansas City Star reports.
James is likely in danger of missing the team's Week 3 game against the Bears, though he hasn't officially been ruled out just yet. The 28-year-old receiver played just three snaps on offense in last week's win over the Jaguars, but he holds an important role on special teams as the Chiefs' top kickoff and punt returner.