NFL Network's Mike Garafolo indicates that Anderson is expected to be out at least a few weeks with a knee injury that NFL Network's Ian Rapoport describes as a bone bruise.
Per Mike Klis of 9News.com, the Broncos should know more about Anderson's status Thursday, but while he is sidelined, Devontae Booker is set to head the team's rushing attack, with Kapri Bibbs presumably set to move up a peg on the team's RB depth chart.