Williams has been elevated from the practice squad ahead of Sunday's game against the Lions.
Williams will take over for Samaje Perine, who will not be activated off the reserve/COVID-19 list in time for Sunday's contest. The 23-year-old made a couple of brief appearances last season when Joe Mixon was sidelined, most notably tallying a 12-carry, three-catch effort as the de-facto starter in Week 14 against the Cowboys. The move essentially guarantees Mixon will be expected to handle his full workload, an important distinction considering he's currently listed as questionable with a nagging ankle injury.