Perine will potentially have to share the backfield with Joe Mixon (ankle) on Sunday against the Packers, as Mixon is active for the contest.
Perine was at one point thought to have a larger role in Week 5, as Mixon suffered an ankle injury last week against Jacksonville and didn't log a single practice as a result. That ultimately won't prevent Mixon from taking the field, but Ian Rapoport of NFL Network did note early Sunday morning that the team's typical RB1 "won't be at 100 percent." Perine has yet to see more than 24 percent of the snap share in any single game this season, but that could be headed for an increase Sunday if there's any truth to Rapoport's assertion.