Mixon will miss Wednesday's practice due to an illness that isn't believed to be COVID-19-related, Marisa Contipelli of the Bengals' official site reports.
Meanwhile, head coach Zac Taylor indicated that the neck issue Mixon dealt with during the team's Week 13 loss to the Chargers isn't a concern, per Kelsey Conway of The Cincinnati Enquirer. With Mixon sidelined Wednesday, Samaje Perine is presumably in line to handle the first-team reps at running back for the Bengals' first Week 14 practice.