Cowing is questionable to return to Sunday's game against New England due to a shoulder injury, Nick Wagoner of ESPN.com reports.
Cowing returned two punts for eight yards but did not see a pass from Brock Purdy before heading to the locker room due to a shoulder injury. Isaac Guerendo could fill in for Cowing as the 49ers' punt returner if the latter is unable to return to Sunday's game.