Marquez was placed on the 15-day injured list Friday, retroactive to April 27, with right elbow inflammation.
Marquez was pulled from his last turn in the Rockies' rotation Wednesday versus the Guardians after experiencing upper-arm discomfort. An MRI taken Thursday showed no structural damage, but the 28-year-old right-hander will need some time off as the elbow inflammation dissipates. Connor Seabold is up from Triple-A Albuquerque in a corresponding move and could be a fill-in option for Marquez.