The Rangers placed Mahle on the 15-day injured list Tuesday with right shoulder tightness.
Mahle allowed four earned runs over three inning during his most recent start Sunday. He'll now be forced to miss several turns through the rotation, as the Rangers have deemed his injury severe enough to warrant a trip to the injured list. Jon Gray (groin) was reinstated from the IL in a corresponding move and will act as Mahle's replacement in Texas' rotation.