Marlins starting pitcher Brad Hand handled the Pirates for five innings. He held them to just four hits and no runs before coming out of the game with a 2-0 lead.
Hand (0-1) threw just 74 pitches and struck out two batters before being yanked out of the game.
The Marlins bullpen blew another late-game lead when Mike Dunn and Sam Dyson combined to allow five earned runs in the seventh inning, giving Hand a no-decision.