Manzardo is out of the lineup for Monday's game against the Rangers.
Rhys Hoskins will draw the start at first base while southpaw Tyler Alexander opens the game for Texas, but the left-handed-hitting Manzardo could replace Hoskins at some point later in the contest once the Rangers send a right-hander to the bump. Manzardo had started each of the Guardians' last 12 games but went just 8-for-42 (.190 average) with 15 strikeouts during that stretch.