Frelick was removed from Friday's game against the Marlins due to right shoulder soreness, Todd Rosiak of the Milwaukee Journal Sentinel reports.
Frelick went 0-for-1 at the plate before his shoulder forced him out of the game in the fifth inning. The severity of his injury is still unknown, but the Brewers could issue another update on his status in the near future. If his absence extends into Saturday, Luis Lara would be the next man up to start in right field for Milwaukee.