Pena is out of the lineup for Friday's game against the Orioles, Chandler Rome of The Athletic reports.
Pena is receiving more regular days off since returning from his hamstring injury at the start of August, with Friday being his third rest day. The 27-year-old is batting .289 (13-for-45) with two doubles, a triple, two homers and two steals in 11 games since being reinstated from the injured list.