Mayfield went 1-for-4 with a solo home run in Thursday's 8-7 extra-innings win over the Mariners.
He has been the primary fill-in at shortstop for Carlos Correa (ribs) but has not done much to replace Correa's offense. The homer, the 28-year-old Mayfield's first as a major leaguer, snapped an 0-for-21 skid.